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Alex Chompff

Surgery After Disease Progression May Still Benefit Select Liver Metastasis Patients

Skip to content The CRC Digest ▸ TREATMENT Surgery After Disease Progression May Still Benefit Select Liver Metastasis Patients A Japanese nationwide study analyzed patients from the Colorectal Cancer Liver Metastasis Database who received chemotherapy. (Annals of Surgical Oncology) This content is informational only and does not constitute medical advice. Always

Lean Body Mass Linked to Oxaliplatin Neuropathy Risk

Skip to content The CRC Digest ♥ LIVING WITH CRC Lean Body Mass Linked to Oxaliplatin Neuropathy Risk A study of colorectal cancer patients receiving adjuvant CAPOX found that lean body mass and sarcopenia may influence the risk of dose-limiting peripheral neuropathy, suggesting current body-surface-area dosing may not account for important

FDA Approves SimpleScreen CRC Blood-Based Screening Test

Skip to content The CRC Digest ● REGULATORY FDA Approves SimpleScreen CRC Blood-Based Screening Test The FDA has approved SimpleScreen CRC, a new blood-based screening test for colorectal cancer, expanding non-invasive screening options. (The ASCO Post) This content is informational only and does not constitute medical advice. Always consult your oncologist

CRC Research Update — August 01, 2026

Today's colorectal cancer research highlights

South Dakota sees shifting trends in early-onset CRC incidence by race

Skip to content The CRC Digest South Dakota sees shifting trends in early-onset CRC incidence by race Analysis of 2007-2022 cancer registry data shows the White population's early-onset CRC incidence rose to 9.6 per 100,000 in 2018-2022, surpassing the American Indian rate and reversing historical patterns.

Deficient mismatch repair is a distinct feature of early-onset CRC in Chinese cohort

Skip to content The CRC Digest Deficient mismatch repair is a distinct feature of early-onset CRC in Chinese cohort Among 4,159 colorectal cancer cases at West China Hospital, early-onset CRC (diagnosed before age 50) showed higher rates of deficient mismatch repair compared to late-onset disease. (Int J Cancer) This

Traditional Chinese Medicine formula shows benefit for chemotherapy side effects in real-world study

Skip to content The CRC Digest ♥ LIVING WITH CRC Traditional Chinese Medicine formula shows benefit for chemotherapy side effects in real-world study In a propensity-matched analysis of 178 colorectal cancer patients, those receiving a standardized TCM formula alongside fluoropyrimidine chemotherapy had reduced gastrointestinal toxicity and improved quality of life compared

Systematic review evaluates treatments for bowel dysfunction after colorectal cancer surgery

Skip to content The CRC Digest ♥ LIVING WITH CRC Systematic review evaluates treatments for bowel dysfunction after colorectal cancer surgery Eight studies examined pharmacological therapies including serotonin receptor antagonists, herbal medicines, diazepam, and Botulinum A toxin for managing bowel dysfunction following sphincter-preserving surgeries. (Adv Pharm Bull) This content is informational

Meta-analysis examines timing of chemotherapy after colorectal cancer surgery

Skip to content The CRC Digest ◆ TRIAL DATA Meta-analysis examines timing of chemotherapy after colorectal cancer surgery A systematic review and meta-analysis evaluated the impact of early versus delayed postoperative chemotherapy on overall survival in colorectal cancer patients, aiming to guide clinical decisions on optimal chemotherapy timing. (J Gastrointest Cancer)

HER2-mutated colorectal cancers show distinct genomic features from HER2-amplified tumors

Skip to content The CRC Digest ◇ RESEARCH HER2-mutated colorectal cancers show distinct genomic features from HER2-amplified tumors Analysis of 4,348 CRC patients found that ERBB2/HER2 mutations occurred in 2.2% and amplifications in 2.0%, with distinct genomic landscapes and clinical characteristics between the two groups. (Oncologist) This