Chinese herbal formulation may shift pMMR tumors toward dMMR-like phenotype

◇ RESEARCH

Preclinical research using mouse models found that Xian-Lian-Jie-Du decoction (XLJDD) may modulate proficient mismatch repair (pMMR) colorectal tumors toward a dMMR-like phenotype, potentially enhancing responsiveness to anti-PD-1 therapy. (Phytomedicine)