Five-year colonoscopy surveillance may be as safe as three-year intervals after high-risk polyp removal

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A European randomized trial compared colonoscopy at 5 years versus 3 years after removal of high-risk adenomas (≥10 mm, high-grade dysplasia, villous features, or 3–10 adenomas), with 10-year colorectal cancer incidence as the primary endpoint. (N Engl J Med)