Gut bacterium Eggerthella lenta linked to liver metastasis via vascular barrier disruption

◇ RESEARCH

Multi-omics analysis of two cohorts comprising 20 healthy controls, 82 non-metastatic CRC patients, and 65 patients with liver or lung metastases found that those with CRC liver metastasis had impaired gut vascular barrier function and bacterial colonization at metastatic sites, with E. lenta enriched in these patients. (Cell Discov)