A narrative review found that immune checkpoint inhibitors for dMMR/MSI-H colorectal cancer may affect reproductive-age women through direct reproductive uncertainty (including endocrine toxicities and hypothesized, but currently unproven, direct gonadal effects) and potential avoidance of pelvic radiotherapy. (J Clin Med)
Immunotherapy May Reshape Fertility Counseling for Young Women with CRC
The CRC Digest