Among 83 patients with metastatic colorectal cancer, mutation frequencies were 47% for KRAS, 14.5% for NRAS, and 6% for BRAF; BRAF mutations were significantly more frequent in patients under 50 years of age. (Middle East Journal of Digestive Diseases)
KRAS, NRAS, and BRAF mutation frequencies reported in Iranian metastatic CRC cohort
The CRC Digest