TRIAL DATA
Long-term results show benefit of chemotherapy after liver metastasis surgery — Journal of Clinical Oncology
The JCOG0603 trial compared hepatectomy (liver surgery) followed by mFOLFOX6 chemotherapy versus hepatectomy alone for patients with liver metastases from colorectal cancer. This phase II/III randomized trial now reports long-term outcomes, providing evidence on whether adjuvant chemotherapy after complete surgical removal of liver metastases improves survival.
What this means
For patients who have colorectal cancer that has spread to the liver and can be surgically removed, this study helps answer whether chemotherapy after surgery provides additional benefit. The long-term results can guide treatment decisions for this patient population.