• TREATMENT

    Radiation plus dual checkpoint blockade evaluated in MSS metastatic disease

    A multi-institution phase II study enrolled patients with microsatellite stable metastatic colorectal cancer previously treated with oxaliplatin, 5-fluorouracil, and irinotecan to receive combined radiation therapy and nivolumab/ipilimumab, with the primary endpoint being objective response rate for unirradiated lesions. (Clin Cancer Res)