Study identifies FAIM2 pathway in cancer-associated fibroblasts linked to immune resistance in MSS colorectal cancer

◇ RESEARCH

Researchers identified Fas apoptotic inhibitory molecule 2 (FAIM2) as a stromal regulator downregulated in microsatellite-stable colorectal cancer, where it inversely correlates with collagen production in cancer-associated fibroblasts and is associated with immune infiltration and patient prognosis. (Mol Cell Biochem)