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crc-research

A collection of 154 issues

Y chromosome loss studied in male metastatic CRC patients

Skip to content The CRC Digest Y chromosome loss studied in male metastatic CRC patients Researchers analyzed tumor-associated loss of the Y chromosome in 91 male patients with metastatic colorectal cancer. (Genes Chromosomes Cancer) This content is informational only and does not constitute medical advice. Always consult your oncologist or

Estrogen receptor may explain gender differences in early-onset CRC

Skip to content The CRC Digest Estrogen receptor may explain gender differences in early-onset CRC A study identified estrogen receptor expression differences between male and female early-onset CRC patients. (Clinical Colorectal Cancer) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team.

Estrogen receptor patterns differ by gender in early-onset CRC

Skip to content The CRC Digest Estrogen receptor patterns differ by gender in early-onset CRC Researchers found distinct estrogen receptor expression patterns between male and female patients with early-onset colorectal cancer. (Clinical Colorectal Cancer) This content is informational only and does not constitute medical advice. Always consult your oncologist or

CRC Research Update — June 15, 2026

Today's colorectal cancer research highlights

Immunotherapy transforms surgical decisions in Lynch syndrome CRC

Skip to content The CRC Digest Immunotherapy transforms surgical decisions in Lynch syndrome CRC Narrative review examines how immune checkpoint inhibitors achieving 60-100% pathological complete response rates in MSI-H/dMMR CRC are challenging traditional recommendations for extensive prophylactic surgery in Lynch syndrome patients. (European Journal of Surgical Oncology) This content

Early-onset CRC presents with distinct symptom patterns

Skip to content The CRC Digest Early-onset CRC presents with distinct symptom patterns National inpatient analysis of 2020-2022 data found that early-onset CRC (diagnosed before age 50) presents with distinct symptom profiles compared to late-onset disease, highlighting the need to identify high-risk individuals beyond current screening criteria. (Cancer Treatment and

CRC Research Finding

Skip to content The CRC Digest ◇ Loss of Y chromosome in primary tumors analyzed in metastatic CRC patients A retrospective study of 91 male patients with metastatic CRC examined tumor-associated loss of the Y chromosome (LoY) and its associations with KRAS/BRAF mutation status and patient outcomes. (Genes Chromosomes Cancer)

CRC Research Update — June 10, 2026

Today's colorectal cancer research highlights

BRAF V600E screening identifies candidates for perioperative therapy

Skip to content The CRC Digest BRAF V600E screening identifies candidates for perioperative therapy Multicenter screening evaluated preoperative BRAF V600E mutation detection in patients with resectable colorectal oligometastases, enabling recruitment to a trial of the BEACON triplet regimen. (Int J Clin Oncol) This content is informational only and does not

Shared decision-making training increases screening options

Skip to content The CRC Digest Shared decision-making training increases screening options A cluster randomized trial in Switzerland found that training primary care physicians in shared decision-making promoted offering both colonoscopy and FOBT for CRC screening. (PLoS One) This content is informational only and does not constitute medical advice. Always