Sign in Subscribe

crc-research

A collection of 715 issues

Case series documents bowel stenosis following immunotherapy in dMMR colorectal cancer

Skip to content The CRC Digest ♥ LIVING WITH CRC Case series documents bowel stenosis following immunotherapy in dMMR colorectal cancer A case series documents bowel stenosis following immunotherapy in patients with mismatch repair deficient colorectal cancer. (Clinical Colorectal Cancer) This content is informational only and does not constitute medical advice.

Incisional hernia impacts quality of life years after colorectal cancer surgery

Skip to content The CRC Digest ♥ LIVING WITH CRC Incisional hernia impacts quality of life years after colorectal cancer surgery The Rein4CeTo1 randomized trial evaluated quality of life, abdominal wall pain, and discomfort in patients 1 and 3 years after colorectal cancer surgery, using CT scans to diagnose incisional hernia.

CONFIRM trial examines race, ethnicity, and screening test use among Veterans

Skip to content The CRC Digest ▪ SCREENING CONFIRM trial examines race, ethnicity, and screening test use among Veterans A study of 50,125 US Veteran participants in a randomized trial comparing colonoscopy to annual fecal immunochemical testing examined how race, ethnicity, and access to care factors relate to screening test

Dual immunotherapy shows promise in mismatch repair proficient colon cancer

Skip to content The CRC Digest ◆ TRIAL DATA Dual immunotherapy shows promise in mismatch repair proficient colon cancer The phase 2 NEST trial tested neoadjuvant botensilimab plus balstilimab in patients with resectable colon cancer. The study examined safety, feasibility, and pathologic response before surgical resection. (Clinical Cancer Research) This content

CRC Research Update — August 26, 2026

Today's colorectal cancer research highlights

Case report: POLE mutation combined with dMMR/MSI

Skip to content The CRC Digest ▸ TREATMENT Case report: POLE mutation combined with dMMR/MSI (Am J Ther) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com

SEER data shows 10,395 early-onset CRC cases in 2023

Skip to content The CRC Digest ▪ SCREENING SEER data shows 10,395 early-onset CRC cases in 2023 The study examined whether CRC incidence trends were concentrated among adults newly eligible for screening after the USPSTF lowered the recommended starting age from 50 to 45 years in 2021. (Am J Prev

Single-port versus multi-port robotic surgery for colorectal cancer

Skip to content The CRC Digest ♥ LIVING WITH CRC Single-port versus multi-port robotic surgery for colorectal cancer In a propensity score-matched analysis of 104 patients per group with stage I-III CRC, researchers compared single-port and multi-port robotic surgery. Single-port robotic surgery may reduce incision burden compared with multi-port robotic surgery.

Case report: POLE-mutated, dMMR/MSI colorectal cancer

Skip to content The CRC Digest ▸ TREATMENT Case report: POLE-mutated, dMMR/MSI colorectal cancer (Am J Ther) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com

Gut microbiome profiles improve detection of precancerous lesions in FIT screening

Skip to content The CRC Digest ▪ SCREENING Gut microbiome profiles improve detection of precancerous lesions in FIT screening In a Norwegian study of 1,034 FIT-positive screening participants, combining microbial profiles with quantitative FIT values improved detection of premalignant lesions beyond optimizing the FIT value alone. (Nat Commun) This content