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crc-research

A collection of 723 issues

Pelvic floor rehabilitation addresses bowel dysfunction and quality of life after rectal cancer

Skip to content The CRC Digest Pelvic floor rehabilitation addresses bowel dysfunction and quality of life after rectal cancer Fourteen survivors shared experiences with structured pelvic floor programs that support bowel function recovery and address psychosocial impacts of low anterior resection syndrome. (Support Care Cancer) This content is informational only

Obesity and metabolic dysfunction drive early-onset CRC through inflammation and gut dysbiosis

Skip to content The CRC Digest Obesity and metabolic dysfunction drive early-onset CRC through inflammation and gut dysbiosis Epidemiological evidence links early-life adiposity and persistent metabolic stress to the rising incidence of colorectal cancer before age 50. (Int J Cancer) This content is informational only and does not constitute medical

CRC Research Finding

Skip to content The CRC Digest ♥ Structured pelvic floor rehabilitation helps survivors manage bowel dysfunction after rectal cancer surgery A qualitative study of 14 colorectal cancer survivors found that structured pelvic floor rehabilitation programs address low anterior resection syndrome, a common challenge affecting bowel function, psychosocial health, and daily living

CRC Research Update — June 26, 2026

Today's colorectal cancer research highlights

CRC Research Finding

Skip to content The CRC Digest ♥ Patient-led home-based follow-up maintains quality of life for CRC survivors The DISTANCE trial, a stepped-wedge cluster randomized study of 354 stage I-III CRC survivors, found that patient-led home-based follow-up showed no significant difference in hospital contacts compared to standard follow-up while maintaining quality of

CRC Research Update — June 25, 2026

Today's colorectal cancer research highlights

Colonoscope-Derived Mucus Detects KRAS Mutations in Precancerous Lesions

Skip to content The CRC Digest Colonoscope-Derived Mucus Detects KRAS Mutations in Precancerous Lesions A prospective pilot study found that mucus collected from the colonoscope sheath during routine colonoscopy serves as a high-fidelity source of cell-free DNA for detecting KRAS-mutated colorectal neoplasia. (Translational Oncology) This content is informational only and

KRAS G13C Inhibitor Reveals Unique Biology of Codon 13 Mutations

Skip to content The CRC Digest KRAS G13C Inhibitor Reveals Unique Biology of Codon 13 Mutations RMC-8839, a covalent KRAS G13C inhibitor, induced tumor regressions in selected xenograft models, but one-third of cell lines showed incomplete pathway suppression, revealing that codon 13-mutant RAS differs from other KRAS mutations with decreased

Immunotherapy Shows Response in Pediatric CMMRD-Associated CRC

Skip to content The CRC Digest Immunotherapy Shows Response in Pediatric CMMRD-Associated CRC A 10-year-old with constitutional mismatch repair deficiency-associated colorectal adenocarcinoma received neoadjuvant ipilimumab and nivolumab, achieving partial response. (Journal of Pediatric Hematology/Oncology) This content is informational only and does not constitute medical advice. Always consult your oncologist

FIT Screening Effective in 45-49 Age Group

Skip to content The CRC Digest FIT Screening Effective in 45-49 Age Group A Chinese screening program found comparable detection rates of advanced colorectal neoplasia between adults aged 45-49 and 50-54 years. (American Journal of Gastroenterology) This content is informational only and does not constitute medical advice. Always consult your