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crc-research

A collection of 731 issues

CRC Research Update — April 06, 2026

Today's colorectal cancer research highlights

MSI-H tumor responds to immunotherapy while MSI-stable tumor does not in same patient

Skip to content The CRC Digest MSI-H tumor responds to immunotherapy while MSI-stable tumor does not in same patient Exceptional case of synchronous colon cancers with different MMR status provides direct in vivo evidence of ICI responsiveness differences. (Japanese Journal of Clinical Oncology) This content is informational only and does

ctDNA testing offers noninvasive approach to detect minimal residual disease after surgery

Skip to content The CRC Digest ctDNA testing offers noninvasive approach to detect minimal residual disease after surgery Scoping review examines how circulating tumor DNA can guide adjuvant therapy decisions and surveillance strategies in resected CRC. (Journal of Gastrointestinal Surgery) This content is informational only and does not constitute medical

Fecal hemoglobin testing linked to improved colorectal cancer survival

Skip to content The CRC Digest Fecal hemoglobin testing linked to improved colorectal cancer survival Research suggests that fecal hemoglobin screening may contribute to better survival outcomes in colorectal cancer patients. (Bioengineer.org) This content is informational only and does not constitute medical advice. Always consult your oncologist or care

UAB doctor urges earlier screening as colorectal cancer rises among younger adults

Skip to content The CRC Digest UAB doctor urges earlier screening as colorectal cancer rises among younger adults Physicians emphasize the importance of earlier screening as CRC incidence continues to increase in patients under 50. (WBRC) This content is informational only and does not constitute medical advice. Always consult your

CRC Research Finding

Skip to content The CRC Digest ▪ AI model using CT scans predicts microsatellite instability before surgery in multicenter study A deep learning radiomics model analyzing 873 CRC patients across three medical centers improved preoperative MSI prediction using enhanced CT images and body composition data. (European Journal of Radiology) This content

This Week in CRC Research — April 05, 2026

Weekly colorectal cancer research intelligence

Real-world study identifies factors predicting immunotherapy response in MSI-H/dMMR gastrointestinal cancers

Skip to content The CRC Digest ◆ TRIAL DATA Real-world study identifies factors predicting immunotherapy response in MSI-H/dMMR gastrointestinal cancers — ESMO Real World Data and Digital Oncology A multicenter retrospective study of 122 patients with advanced MSI-H/dMMR (microsatellite instability-high/mismatch repair deficiency) gastrointestinal tumors treated with immune checkpoint inhibitors

Circulating tumor DNA testing after surgery predicts recurrence in stage III colon cancer

Skip to content The CRC Digest ◆ TRIAL DATA Circulating tumor DNA testing after surgery predicts recurrence in stage III colon cancer — Journal of Clinical Oncology Analysis from the phase III Alliance N0147 trial evaluated a tissue-free circulating tumor DNA (ctDNA) assay in patients receiving FOLFOX-based adjuvant chemotherapy after surgery for

Blood-based circulating tumor DNA shows promise for early colorectal cancer detection

Skip to content The CRC Digest ▪ SCREENING Blood-based circulating tumor DNA shows promise for early colorectal cancer detection — Digestive Diseases A systematic review and meta-analysis evaluated the accuracy of blood-based circulating tumor DNA (ctDNA) tests for detecting colorectal cancer in people without symptoms. These tests look for tiny fragments of