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early-onset

A collection of 186 issues

Survey finds low awareness of early-onset colorectal cancer among young adults

Skip to content The CRC Digest ♥ LIVING WITH CRC Survey finds low awareness of early-onset colorectal cancer among young adults A survey of 1,000 people aged 20-44 found only 24% were aware of early-onset colorectal cancer, 29% had not heard of any symptoms, and female respondents felt less comfortable

CRC Research Update — October 14, 2026

Today's colorectal cancer research highlights

Surgically treated early-onset rectal neuroendocrine neoplasms increased from 234 to 778 cases annually

Skip to content The CRC Digest Surgically treated early-onset rectal neuroendocrine neoplasms increased from 234 to 778 cases annually A National Cancer Database analysis of 7,285 patients under 50 who underwent surgery for rectal neuroendocrine neoplasms found that annual cases increased from 234 in 2004 to 778 in 2023,

National survey finds provider barriers to early-onset CRC diagnosis

Skip to content The CRC Digest National survey finds provider barriers to early-onset CRC diagnosis A national survey of 277 U.S. healthcare providers found that although 87% were concerned about early-onset colorectal cancer, approximately one-half reported that younger adults commonly experienced symptoms for four months or longer before seeking

CRC Research Update — October 13, 2026

Today's colorectal cancer research highlights

Delays in starting treatment linked to higher mortality in early-onset colorectal cancer

Skip to content The CRC Digest ♥ LIVING WITH CRC Delays in starting treatment linked to higher mortality in early-onset colorectal cancer A National Cancer Database study of 56,333 patients under 45 found that increased time to treatment initiation was associated with worse survival, with disparities in treatment delays identified

CRC Research Update — October 12, 2026

Today's colorectal cancer research highlights

P-selectin glycoprotein ligand-1 may link early- and late-onset colorectal cancer pathways

Skip to content The CRC Digest ◇ RESEARCH P-selectin glycoprotein ligand-1 may link early- and late-onset colorectal cancer pathways A review proposes that PSGL-1, a molecule involved in chronic gut inflammation, may function as a molecular bridge between early-onset and late-onset colorectal cancer, offering insight into shared pathophysiological mechanisms. (Biomed Pharmacother)

CRC Research Update — October 11, 2026

Today's colorectal cancer research highlights

Epigenetic exposure signatures distinguish early-onset from later-onset CRC

Skip to content The CRC Digest Epigenetic exposure signatures distinguish early-onset from later-onset CRC Researchers computed methylation risk scores across lifestyle, air pollution, and pesticide exposome traits in 146 participants from the DANCE cohort to identify long-term exposures that may contribute to early-onset colorectal cancer risk. (medRxiv preprint) This content