CRC Research Update — October 10, 2026
Today's colorectal cancer research highlights
early-onset
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Prediction model for bowel prep quality in patients ≤50
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The CRC Digest
Prediction model for bowel prep quality in patients ≤50
Researchers developed and internally validated a prediction model for suboptimal bowel preparation in 2,283 individuals aged ≤50 years undergoing colonoscopy, using the Boston Bowel Preparation Scale. (Front Med)
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Polyp detection in under-45 diagnostic colonoscopy
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The CRC Digest
Polyp detection in under-45 diagnostic colonoscopy
A retrospective study of 727 patients aged 18-44 undergoing non-screening colonoscopy evaluated histologically confirmed colorectal polyps and examined predictors including age, sex, and BMI. (Cureus)
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CRC Research Update — October 06, 2026
Today's colorectal cancer research highlights
Accelerated biological aging linked to increased early-onset colorectal cancer risk
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The CRC Digest
Accelerated biological aging linked to increased early-onset colorectal cancer risk
A prospective cohort of 198,491 Korean adults under 50 found that biological age, estimated from nine routine blood biomarkers, was associated with early-onset colorectal adenocarcinoma risk, suggesting biological aging may serve as a
CRC Research Update — October 05, 2026
Today's colorectal cancer research highlights
RTK-RAS pathway alterations show age-dependent clinical significance in colorectal cancer
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The CRC Digest
◇ RESEARCH
RTK-RAS pathway alterations show age-dependent clinical significance in colorectal cancer
RTK-RAS alterations have been associated with unfavorable survival in untreated early-onset non-Hispanic White colorectal cancer, while an opposite association has been observed in FOLFOX-treated late-onset disease. (Journal of Cancer Biology)
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CRC Research Update — October 03, 2026
Today's colorectal cancer research highlights
Qualitative review maps illness experiences and supportive care needs in early-onset CRC
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The CRC Digest
Qualitative review maps illness experiences and supportive care needs in early-onset CRC
Systematic review synthesizes challenges faced by patients diagnosed before age 50 during critical periods of relationship formation, family building, and career development. (J Clin Nurs)
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Early-onset CRC shows distinct genomic landscape in dual-cohort analysis
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The CRC Digest
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Early-onset CRC shows distinct genomic landscape in dual-cohort analysis
Analysis of TCGA PanCancer Atlas and MSK-IMPACT 50K cohorts reveals reproducible mutational differences in colorectal cancer diagnosed before age 50, with implications for biomarker-driven treatment. (PLoS One)
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