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early-onset

A collection of 186 issues

What Causes Colorectal Cancer in the Young?

Skip to content The CRC Digest What Causes Colorectal Cancer in the Young? An age-specific attributable fraction analysis estimated population attributable fractions for lifestyle and medical risk factors across three age groups (30-49, 50-69, and ≥70 years), using birth-cohort-specific prevalence data from NHANES 1999-2002 and CRC incidence from Global Cancer

CRC Research Update — September 19, 2026

Today's colorectal cancer research highlights

Machine learning models tested for mortality prediction in Tennessee early-onset CRC patients

Skip to content The CRC Digest Machine learning models tested for mortality prediction in Tennessee early-onset CRC patients A retrospective study of 3,467 Tennessee patients aged 20–49 compared machine learning algorithms for predicting all-cause mortality and 1-, 3-, and 5-year mortality. (Cancer Epidemiol) This content is informational only

German trial to test invitation strategies for CRC screening in adults under 50

Skip to content The CRC Digest German trial to test invitation strategies for CRC screening in adults under 50 The PETER trial will assess the effect of postal and digital invitations and reminders on faecal immunochemical test use and early detection among younger adults. (BMJ Open) This content is informational

CRC Research Update — September 16, 2026

Today's colorectal cancer research highlights

Screening strategies may not adequately address early-onset CRC burden

Skip to content The CRC Digest Screening strategies may not adequately address early-onset CRC burden A systematic review found uncertainty remains regarding whether current screening strategies adequately address the diagnostic burden of early-onset colorectal cancer, defined as diagnosis before age 50. (Cancer Epidemiol) This content is informational only and does

Systematic review finds screening gaps in early-onset colorectal cancer despite lowered age thresholds

Skip to content The CRC Digest ▪ SCREENING Systematic review finds screening gaps in early-onset colorectal cancer despite lowered age thresholds A systematic review of population-based screening studies found that current strategies may not adequately address the diagnostic burden of colorectal cancer in adults younger than 50, even as several countries

CRC Research Update — September 15, 2026

Today's colorectal cancer research highlights

Early-onset and average-onset metastatic colorectal cancer share similar genomic landscapes

Skip to content The CRC Digest ◇ RESEARCH Early-onset and average-onset metastatic colorectal cancer share similar genomic landscapes An analysis of 1,892 patients found that major driver alterations. TP53, APC, and KRAS — occurred at comparable frequencies in metastatic colorectal cancer diagnosed before age 50 versus later, suggesting the diseases are

CRC Research Update — September 14, 2026

Today's colorectal cancer research highlights