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early-onset

A collection of 127 issues

Financial and professional impacts persist for early-onset CRC survivors

Skip to content The CRC Digest Financial and professional impacts persist for early-onset CRC survivors A multicenter study across 7 academic medical centers found that patients diagnosed with colorectal cancer before age 50 experience lasting financial and professional instability, given their developmental stage in establishing careers and families. (Diseases of

CRC Research Update — August 03, 2026

Today's colorectal cancer research highlights

Symptom Identification Critical for Adults 18-44

Skip to content The CRC Digest Symptom Identification Critical for Adults 18-44 Adults under 45 without access to average-risk screening require a well-defined system for symptom identification and workup to avoid diagnostic delays and worse outcomes. (Cancer Epidemiology, Biomarkers & Prevention) This content is informational only and does not constitute

Study Examines Symptoms as Diagnostic Indicators in Adults Under 45

Skip to content The CRC Digest ▪ SCREENING Study Examines Symptoms as Diagnostic Indicators in Adults Under 45 (Cancer Epidemiology, Biomarkers & Prevention) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com

CRC Research Update — August 01, 2026

Today's colorectal cancer research highlights

South Dakota sees shifting trends in early-onset CRC incidence by race

Skip to content The CRC Digest South Dakota sees shifting trends in early-onset CRC incidence by race Analysis of 2007-2022 cancer registry data shows the White population's early-onset CRC incidence rose to 9.6 per 100,000 in 2018-2022, surpassing the American Indian rate and reversing historical patterns.

Deficient mismatch repair is a distinct feature of early-onset CRC in Chinese cohort

Skip to content The CRC Digest Deficient mismatch repair is a distinct feature of early-onset CRC in Chinese cohort Among 4,159 colorectal cancer cases at West China Hospital, early-onset CRC (diagnosed before age 50) showed higher rates of deficient mismatch repair compared to late-onset disease. (Int J Cancer) This

CRC Research Update — July 28, 2026

Today's colorectal cancer research highlights

Immunotherapy May Reshape Fertility Counseling for Young Women with CRC

Skip to content The CRC Digest Immunotherapy May Reshape Fertility Counseling for Young Women with CRC A narrative review found that immune checkpoint inhibitors for dMMR/MSI-H colorectal cancer may affect reproductive-age women through direct reproductive uncertainty (including endocrine toxicities and hypothesized, but currently unproven, direct gonadal effects) and potential

Canadian Symposium Highlights Care Gaps for Early-Onset Cancer Patients

Skip to content The CRC Digest Canadian Symposium Highlights Care Gaps for Early-Onset Cancer Patients The 2025 Early Age Onset Cancer Symposium identified critical gaps including diagnostic delays, screening eligibility criteria that no longer reflect current disease epidemiology, and insufficient age-appropriate infrastructure for patients under 50. (Curr Oncol) This content