CRC Research Update — July 19, 2026
Today's colorectal cancer research highlights
early-onset
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Case-control study compares metabolic and laboratory biomarkers in early-onset versus late-onset colorectal cancer
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The CRC Digest
Case-control study compares metabolic and laboratory biomarkers in early-onset versus late-onset colorectal cancer
Researchers used a large US database to compare metabolic, inflammatory, and laboratory abnormalities between patients diagnosed at ages 18-49 versus 50-75. (Cancers)
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First Nations people in Ontario experience higher colon cancer incidence at younger ages
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The CRC Digest
First Nations people in Ontario experience higher colon cancer incidence at younger ages
New evidence shows registered First Nations people have higher colon cancer incidence at younger ages and poorer survival after breast, cervical, and colon cancer diagnoses than other Ontario residents. (The Lancet
CRC Research Update — July 18, 2026
Today's colorectal cancer research highlights
Salivary microbiome evaluated as non-invasive screening tool for early-onset CRC
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Salivary microbiome evaluated as non-invasive screening tool for early-onset CRC
High-throughput 16S ribosomal RNA gene sequencing of saliva samples showed distinct microbiota profiles in EOCRC patients compared to controls. (BMC Microbiol)
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Salivary microbiome profiles distinguish early-onset CRC patients from healthy controls
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The CRC Digest
Salivary microbiome profiles distinguish early-onset CRC patients from healthy controls
Researchers collected saliva samples from 65 EOCRC patients and 63 controls, profiling the microbiota and developing screening models using machine learning algorithms. (BMC Microbiol)
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Alabama study examines lifestyle and metabolic factors in early- vs late-onset CRC
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Alabama study examines lifestyle and metabolic factors in early- vs late-onset CRC
A retrospective study from 2010–2023 investigated whether associations between lifestyle factors (smoking, BMI) and clinical factors (type 2 diabetes, hypertension, hyperlipidemia) and age at CRC diagnosis differed by race. (Cancer Causes
Meta-analysis projects rising early-onset CRC burden through 2030
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Meta-analysis projects rising early-onset CRC burden through 2030
A systematic review and meta-analysis evaluated early-onset colorectal cancer (diagnosed under age 50) incidence and temporal trends from 1990 to 2021, identifying associated risk factors and projecting burden through 2030. (Cureus)
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CRC Research Update — July 17, 2026
Today's colorectal cancer research highlights
CRC Research Update — July 16, 2026
Today's colorectal cancer research highlights