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epidemiology

A collection of 22 issues

Study Examines Symptoms as Diagnostic Indicators in Adults Under 45

Skip to content The CRC Digest ▪ SCREENING Study Examines Symptoms as Diagnostic Indicators in Adults Under 45 (Cancer Epidemiology, Biomarkers & Prevention) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com

South Dakota sees shifting trends in early-onset CRC incidence by race

Skip to content The CRC Digest South Dakota sees shifting trends in early-onset CRC incidence by race Analysis of 2007-2022 cancer registry data shows the White population's early-onset CRC incidence rose to 9.6 per 100,000 in 2018-2022, surpassing the American Indian rate and reversing historical patterns.

Polyp Risk Rises with Age in Young Adults, Study Finds

Skip to content The CRC Digest Polyp Risk Rises with Age in Young Adults, Study Finds A retrospective colonoscopy study of 3,959 adults aged 18-44 used Joinpoint regression to identify age inflection points for polyp detection rates, with detection rates for polyps, adenomas, and serrated lesions all rising significantly

End-of-Life Care Trends Show Shift Toward Home and Hospice

Skip to content The CRC Digest End-of-Life Care Trends Show Shift Toward Home and Hospice Among 75,428 early-onset CRC decedents from 1999-2020, the proportion dying at home or hospice facilities increased from 48.3% to 66.6%, though disparities persist for Black patients. (Journal of Gastrointestinal Cancer) This content

MSI-H/dMMR Prevalence Documented in Japanese CRC Registry

Skip to content The CRC Digest MSI-H/dMMR Prevalence Documented in Japanese CRC Registry A multicenter study of 1,464 Japanese patients with primary colorectal cancer enrolled from April 2024 to March 2025 investigated the frequency and features of MSI-H/dMMR tumors to support personalized treatment strategies. (Annals of Gastroenterological

First Nations people in Ontario experience higher colon cancer incidence at younger ages

Skip to content The CRC Digest First Nations people in Ontario experience higher colon cancer incidence at younger ages New evidence shows registered First Nations people have higher colon cancer incidence at younger ages and poorer survival after breast, cervical, and colon cancer diagnoses than other Ontario residents. (The Lancet

Early-Onset CRC Rising Across Europe with Regional Disparities

Skip to content The CRC Digest Early-Onset CRC Rising Across Europe with Regional Disparities Incidence of colorectal cancer in people under 50 is rising across Europe, with stark regional differences in incidence and mortality; early-onset disease shows a predominance for distal tumors and aggressive features. (European Journal of Cancer) This

Obesity and metabolic dysfunction drive early-onset CRC through inflammation and gut dysbiosis

Skip to content The CRC Digest Obesity and metabolic dysfunction drive early-onset CRC through inflammation and gut dysbiosis Epidemiological evidence links early-life adiposity and persistent metabolic stress to the rising incidence of colorectal cancer before age 50. (Int J Cancer) This content is informational only and does not constitute medical

CRC Research Finding

Skip to content The CRC Digest ▪ Black men in Louisiana show low colorectal cancer screening awareness despite high risk A statewide survey of Black men aged 30-44 in Louisiana found limited awareness of screening guidelines, low perceived risk, and structural barriers to care, highlighting the need for targeted interventions in

Early-onset CRC presents with distinct symptom patterns

Skip to content The CRC Digest Early-onset CRC presents with distinct symptom patterns National inpatient analysis of 2020-2022 data found that early-onset CRC (diagnosed before age 50) presents with distinct symptom profiles compared to late-onset disease, highlighting the need to identify high-risk individuals beyond current screening criteria. (Cancer Treatment and