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kras

A collection of 71 issues

Kazakhstan Study Links KRAS Mutation Detection Methods to Survival in Stage II-IV CRC

Skip to content The CRC Digest ◇ RESEARCH Kazakhstan Study Links KRAS Mutation Detection Methods to Survival in Stage II-IV CRC A 332-patient cohort study compared KRAS variant detection by real-time and digital PCR in tumor tissue and plasma, examining associations with overall survival across stage II-IV disease. (Genes) This content

Kazakhstani pilot study profiles KRAS and BRAF mutations using NGS and ddPCR

Skip to content The CRC Digest Kazakhstani pilot study profiles KRAS and BRAF mutations using NGS and ddPCR Researchers used targeted next-generation sequencing and droplet digital PCR to characterize KRAS and BRAF mutations in metastatic colorectal cancer patients from Kazakhstan, where molecular epidemiological data remain limited. (Frontiers in Medicine) This

CRC Research Update — August 26, 2026

Today's colorectal cancer research highlights

CRC Research Update — August 22, 2026

Today's colorectal cancer research highlights

Disrupting KRAS-AGO2 interaction may sensitize KRAS-mutant CRC to therapy

Skip to content The CRC Digest Disrupting KRAS-AGO2 interaction may sensitize KRAS-mutant CRC to therapy Preclinical research developed peptide-gold nanoparticles that disrupt the interaction between mutated KRAS and AGO2, potentially sensitizing KRAS-mutated colorectal cancer to chemo-immunotherapy. (Apoptosis) This content is informational only and does not constitute medical advice. Always consult

Selenium nanoparticles selectively target KRAS G13D mutation

Skip to content The CRC Digest ◇ RESEARCH Selenium nanoparticles selectively target KRAS G13D mutation Researchers developed selenium nanoparticles that specifically inhibit tumors driven by the KRAS G13D mutation—a variant that currently has no approved targeted therapies—by upregulating the tumor suppressor GPX2 and blocking metastasis pathways. (Advanced Science) This

CRC Research Update — August 20, 2026

Today's colorectal cancer research highlights

CRC Research Update — August 15, 2026

Today's colorectal cancer research highlights

New gene circuit platform targets multiple KRAS mutations in preclinical models

Skip to content The CRC Digest ◇ RESEARCH New gene circuit platform targets multiple KRAS mutations in preclinical models Researchers developed a platform that enables in vivo self-assembly of small extracellular vesicles encapsulating KRAS-specific siRNAs for broad targeting of KRAS mutants, showing activity in orthotopic models of KRAS G12D-, G12V-, and

CRC Research Update — August 14, 2026

Today's colorectal cancer research highlights