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liver-mets

A collection of 85 issues

Study identifies risk factors for irinotecan liver toxicity

Skip to content The CRC Digest ♥ LIVING WITH CRC Study identifies risk factors for irinotecan liver toxicity A retrospective study of 229 cancer patients receiving irinotecan chemotherapy identified key risk factors for hepatotoxicity, which could help clinicians monitor and manage this side effect more effectively. (Frontiers in Oncology) This content

CRC Research Update — August 20, 2026

Today's colorectal cancer research highlights

Australian registry study examines treatment patterns in early-onset CRC with liver metastases

Skip to content The CRC Digest ◇ RESEARCH Australian registry study examines treatment patterns in early-onset CRC with liver metastases A retrospective cohort study using the TRACC registry explored treatment timing, sequencing, and outcomes for early-onset CRC patients (≤50 years) with liver-only metastases compared to late-onset patients. (Med J Aust) This

CRC Research Update — August 14, 2026

Today's colorectal cancer research highlights

KRAS Mutations and Liver Metastases Predict Worse Outcomes in Third-Line Metastatic CRC

Skip to content The CRC Digest ◇ RESEARCH KRAS Mutations and Liver Metastases Predict Worse Outcomes in Third-Line Metastatic CRC A pooled analysis of placebo-controlled trials from the ARCAD CRC Database found that KRAS mutations and liver metastases are independently associated with poorer prognosis in patients receiving third-line therapy for metastatic

CRC Research Update — August 07, 2026

Today's colorectal cancer research highlights

Meta-analysis compares EGFR inhibitors versus bevacizumab for converting unresectable liver metastases

Skip to content The CRC Digest ▸ TREATMENT Meta-analysis compares EGFR inhibitors versus bevacizumab for converting unresectable liver metastases A systematic review and meta-analysis of randomized trials in patients with RAS wild-type colorectal liver metastases compared chemotherapy combined with EGFR inhibitors versus bevacizumab as first-line treatment, analyzing data from 795 patients

CRC Research Update — August 02, 2026

Today's colorectal cancer research highlights

Surgery After Disease Progression May Still Benefit Select Liver Metastasis Patients

Skip to content The CRC Digest ▸ TREATMENT Surgery After Disease Progression May Still Benefit Select Liver Metastasis Patients A Japanese nationwide study analyzed patients from the Colorectal Cancer Liver Metastasis Database who received chemotherapy. (Annals of Surgical Oncology) This content is informational only and does not constitute medical advice. Always

Medicaid Expansion Linked to Lower Mortality in Metastatic CRC

Skip to content The CRC Digest ♥ LIVING WITH CRC Medicaid Expansion Linked to Lower Mortality in Metastatic CRC A SEER database analysis found that Medicaid expansion was associated with decreased mortality in patients younger than 65 diagnosed with colorectal cancer and synchronous liver metastasis. (Annals of Surgery) This content is