HIPEC combined with surgery and systemic therapy may improve outcomes in peritoneal metastases Skip to content The CRC Digest ▸ TREATMENT HIPEC combined with surgery and systemic therapy may improve outcomes in peritoneal metastases An updated meta-analysis of 12 studies (including 2 randomized controlled trials) encompassing more than 2,700 patients found that hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery and systemic therapy
Prophylactic HIPEC analyzed for survival outcomes in locally advanced colorectal cancer Skip to content The CRC Digest ▸ TREATMENT Prophylactic HIPEC analyzed for survival outcomes in locally advanced colorectal cancer A meta-analysis of 2,023 patients analyzed prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced colorectal cancer, extracting and pooling data to analyze peritoneal metastasis-free survival, disease-free survival, and overall survival.
Phase III trial finds no survival benefit from adding chemotherapy to surgery for peritoneal metastases Skip to content The CRC Digest ◆ TRIAL DATA Phase III trial finds no survival benefit from adding chemotherapy to surgery for peritoneal metastases The CAIRO6 trial (351 patients) found that perioperative systemic therapy did not significantly improve overall survival compared to surgery alone in patients with resectable peritoneal-only metastases (44