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pilot

A collection of 4 issues

CRC Research Finding

Skip to content The CRC Digest ♥ Phone-Based Patient Navigation Tested to Improve Genetic Testing Access A pilot randomized trial in an academic health system evaluated whether offering newly diagnosed CRC patients free, phone-based patient navigation increased rates of referral, counseling, and germline genetic testing compared to usual care. The study

Encorafenib and cetuximab re-challenge combined with nivolumab in BRAF-mutated colorectal cancer

Skip to content The CRC Digest ▸ TREATMENT Encorafenib and cetuximab re-challenge combined with nivolumab in BRAF-mutated colorectal cancer — Clinical Colorectal Cancer A case report from the AGMT mCRC Registry documented successful encorafenib and cetuximab re-challenge combined with nivolumab in BRAF V600E mutated, mismatch-repair-proficient metastatic colorectal cancer. If you have BRAF

CRC Research Finding

Skip to content The CRC Digest ◇ Mismatch repair-deficient CRC with bowel obstruction shows excellent response to immunotherapy A case series reports that patients with mismatch repair-deficient (dMMR) colorectal cancer presenting with bowel obstruction achieved excellent responses to immunotherapy. (Annals of Coloproctology) This content is informational only and does not constitute

Blood-based DNA methylation test shows promise for early detection

Skip to content The CRC Digest Blood-based DNA methylation test shows promise for early detection A pilot study of 50 participants in Gaza evaluated circulating tumor DNA methylation biomarkers (SEPT9, SPG20, ALX4, MGMT, and RASSF1A) for non-invasive colorectal cancer detection, with multi-gene panels showing improved diagnostic performance. (Clinica Chimica Acta)