Testing immunotherapy combination in MSS metastatic colorectal cancer Skip to content The CRC Digest ◆ TRIAL DATA Testing immunotherapy combination in MSS metastatic colorectal cancer — Clinical Colorectal Cancer A Phase II study of pembrolizumab plus capecitabine and bevacizumab for microsatellite stable/mismatch repair-proficient metastatic colorectal cancer. Most colorectal cancers are MSS/pMMR and don't respond well to
Adding immunotherapy to chemotherapy before surgery in stage III colon cancer Skip to content The CRC Digest ◆ TRIAL DATA Adding immunotherapy to chemotherapy before surgery in stage III colon cancer — Clinical Colorectal Cancer The AZUR-4 trial is a Phase 2, open label, randomized study of neoadjuvant dostarlimab plus CAPEOX versus CAPEOX in previously untreated T4N0 or stage III mismatch repair proficient/
CRC Research Finding Skip to content The CRC Digest ◇ MMR Protein Expression Patterns Vary by Patient Characteristics A study of 80 Chinese CRC patients examined how deficient mismatch repair status relates to clinical features, providing insights into this key molecular subtype that affects immunotherapy response. (Front Med) This content is informational only and
CRC Research Finding Skip to content The CRC Digest ▸ Cell Therapy Shows Promise in Third-Line MSS Colorectal Cancer A phase 2B trial evaluated AlloStim®, an allogeneic activated memory Th1 cell therapy designed to convert "cold" tumors to "hot," in third-line MSS/pMMR metastatic colorectal cancer patients. (Translational Oncology) This