Sign in Subscribe

precancer

A collection of 137 issues

Systematic review finds screening gaps in early-onset colorectal cancer despite lowered age thresholds

Skip to content The CRC Digest ▪ SCREENING Systematic review finds screening gaps in early-onset colorectal cancer despite lowered age thresholds A systematic review of population-based screening studies found that current strategies may not adequately address the diagnostic burden of colorectal cancer in adults younger than 50, even as several countries

CRC Research Update — September 15, 2026

Today's colorectal cancer research highlights

AI-assisted colonoscopy systems standardize polyp detection accuracy

Skip to content The CRC Digest ▪ SCREENING AI-assisted colonoscopy systems standardize polyp detection accuracy Computer-aided detection and diagnosis systems using deep learning convolutional neural networks reduce inter-operator variability in adenoma detection rates and help identify diminutive and morphologically subtle lesions. (Journal of Clinical Medicine) This content is informational only and

CRC Research Update — September 14, 2026

Today's colorectal cancer research highlights

Seven-Year Study Maps Dysplasia Patterns in Sessile Serrated Lesions

Skip to content The CRC Digest ▪ SCREENING Seven-Year Study Maps Dysplasia Patterns in Sessile Serrated Lesions A retrospective analysis of all sessile serrated lesions from a single high-detection-rate endoscopist in Australia assessed the prevalence and anatomical distribution of dysplasia, a critical stage in progression to colorectal cancer. (Gastroenterology and Hepatology

CRC Research Update — September 13, 2026

Today's colorectal cancer research highlights

CRC Research Update — September 12, 2026

Today's colorectal cancer research highlights

39-year-old proband with Lynch syndrome shows discordant tumor testing

Skip to content The CRC Digest ◇ RESEARCH 39-year-old proband with Lynch syndrome shows discordant tumor testing A 39-year-old man with colorectal cancer and family history fulfilling Amsterdam criteria carried the germline MLH1 c.931A>G variant, with tumors showing MSI-H status despite retained MMR protein expression. (Clinical Case Reports)

Lynch syndrome family shows MSI-H tumors despite preserved MMR protein staining

Skip to content The CRC Digest ◇ RESEARCH Lynch syndrome family shows MSI-H tumors despite preserved MMR protein staining A family carrying germline MLH1 c.931A>G presented with colorectal tumors showing retained mismatch repair protein expression by immunohistochemistry but microsatellite instability-high status on sequencing, highlighting that preserved staining does

Study evaluates follow-up after positive stool-based screening in rural populations

Skip to content The CRC Digest ▪ SCREENING Study evaluates follow-up after positive stool-based screening in rural populations (The American Surgeon) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com