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precancer

A collection of 138 issues

AI-assisted colonoscopy cost-effectiveness study evaluates financial impact in Singapore

Skip to content The CRC Digest ▪ SCREENING AI-assisted colonoscopy cost-effectiveness study evaluates financial impact in Singapore Computer-assisted detection (CADe) during screening colonoscopy improves adenoma detection rates while reducing endoscopists' mental fatigue. (Int J Surg) This content is informational only and does not constitute medical advice. Always consult your oncologist

First Colombian report of MUTYH-associated polyposis with novel mutations

Skip to content The CRC Digest ◇ RESEARCH First Colombian report of MUTYH-associated polyposis with novel mutations Case series from Colombia's Tolima Grande region describes individuals carrying pathogenic MUTYH variants c.452A>G and c.1353_1355del associated with polyposis phenotypes and colorectal cancer predisposition. (Frontiers in Oncology)

CRC Research Update — September 01, 2026

Today's colorectal cancer research highlights

Digital Platform Validated for Colorectal Cancer Risk Stratification and Personalized Screening Recommendations

Skip to content The CRC Digest Digital Platform Validated for Colorectal Cancer Risk Stratification and Personalized Screening Recommendations Validation study of ChequeáTuColon, a digital tool designed to stratify colorectal cancer risk, detect alarm symptoms, and provide personalized guideline-based screening recommendations, shows accuracy when compared to expert gastroenterologist assessments. (Digestive Diseases

Blood-Based Immune Profiling Identifies Circulating Th1-Like Cells as Biomarker for Advanced Adenomas

Skip to content The CRC Digest Blood-Based Immune Profiling Identifies Circulating Th1-Like Cells as Biomarker for Advanced Adenomas Prospective study of 104 FOBT-positive patients used spectral cytometry and machine learning to identify circulating Th1-like cells as a potential blood biomarker to improve detection of advanced colorectal adenomas and optimize colonoscopy

Structured Surveillance in Lynch Syndrome Shows Effectiveness and Identifies Unmet Needs

Skip to content The CRC Digest Structured Surveillance in Lynch Syndrome Shows Effectiveness and Identifies Unmet Needs Retrospective analysis of 517 Lynch syndrome carriers undergoing structured multiorgan surveillance over 4,827 person-years reports cancer incidence rates, tumor distribution, and modes of detection to assess adherence and effectiveness of guideline-based follow-up.

Immunotherapy Combination Achieves Complete Response and Polyp Regression in dMMR Colorectal Cancer

Skip to content The CRC Digest Immunotherapy Combination Achieves Complete Response and Polyp Regression in dMMR Colorectal Cancer Case report from the NOUS-209-01 trial describes a patient with mismatch repair-deficient colorectal cancer who achieved complete pathologic response and significant colonic polyp regression following treatment with Nous-209 plus pembrolizumab. (Journal of

Scoping Review Identifies Barriers to Diagnostic Colonoscopy After Positive Stool-Based Screening

Skip to content The CRC Digest ▪ SCREENING Scoping Review Identifies Barriers to Diagnostic Colonoscopy After Positive Stool-Based Screening Systematic review synthesizes barriers and facilitators to completing diagnostic colonoscopy after a positive non-invasive stool-based screening test (FIT, gFOBT, or multitarget stool DNA), emphasizing that timely follow-up colonoscopy is essential for reducing

CRC Research Update — August 28, 2026

Today's colorectal cancer research highlights

Australian audit finds gaps in surveillance colonoscopy guideline adherence

Skip to content The CRC Digest ▪ SCREENING Australian audit finds gaps in surveillance colonoscopy guideline adherence A clinical audit of six Victorian public hospitals assessed concordance of endoscopist-recommended surveillance colonoscopy intervals with 2018 Australian Cancer Council guidelines, identifying opportunities to improve adherence. (Australian Health Review) This content is informational only