Serbian cohort reveals MLH1 as predominant Lynch syndrome variant Skip to content The CRC Digest Serbian cohort reveals MLH1 as predominant Lynch syndrome variant Germline testing of 176 high-risk individuals in Serbia identified pathogenic variants predominantly in MLH1, highlighting the need for population-specific genetic testing strategies in hereditary colorectal cancer screening. (Int J Mol Sci) This content is informational
Blood test shows promise for detecting advanced adenomas and colorectal cancer Skip to content The CRC Digest ▪ SCREENING Blood test shows promise for detecting advanced adenomas and colorectal cancer The DENEB study developed and evaluated a novel blood-based assay designed to detect both advanced adenomas and colorectal cancer, addressing a key limitation of current blood tests by targeting premalignant lesions essential
Cancer Survivors Face Elevated Risk of Developing Colorectal Cancer Skip to content The CRC Digest ♥ LIVING WITH CRC Cancer Survivors Face Elevated Risk of Developing Colorectal Cancer A Canadian cohort study of 172,928 non-colorectal cancer survivors found they have an elevated risk of developing subsequent primary colorectal cancers compared to the cancer-free population, suggesting tailored screening approaches may
13-year NordICC trial data Skip to content The CRC Digest ▪ SCREENING 13-year NordICC trial data (Gastroenterology) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com
National study examines surveillance colonoscopy in Lynch syndrome patients Skip to content The CRC Digest ▪ SCREENING National study examines surveillance colonoscopy in Lynch syndrome patients A national study of 4,732 Lynch syndrome carriers in the English NHS assessed adherence to surveillance guidelines and aimed to determine the impact of colonoscopic surveillance on colorectal cancer incidence and mortality in