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prospective

A collection of 92 issues

Quality of life in CRC patients linked to their caregivers' well-being

Skip to content The CRC Digest Quality of life in CRC patients linked to their caregivers' well-being A multicenter study of 119 patient-caregiver dyads found an association between patients' and caregivers' health-related quality of life scores. (Adv Ther) This content is informational only and does not constitute

Oxaliplatin-Induced Neuropathy Tracked in Survivors Up to 2 Years Post-Treatment

Skip to content The CRC Digest ♥ LIVING WITH CRC Oxaliplatin-Induced Neuropathy Tracked in Survivors Up to 2 Years Post-Treatment A prospective study of 106 stage II-III colon cancer patients treated with adjuvant CAPOX examined associations between oxaliplatin dosing and chemotherapy-induced peripheral neuropathy, with assessments continuing up to 24 months after

ctDNA in the Management of Resectable & Advanced Colorectal Cancer

Skip to content The CRC Digest ◇ RESEARCH ctDNA in the Management of Resectable & Advanced Colorectal Cancer A structured narrative review synthesizes evidence on circulating tumor DNA as a biomarker for molecular residual disease after curative-intent treatment, covering tumor-informed and tumor-agnostic assay strategies, postoperative sampling, and serial versus landmark testing

Real-Time AI-Assisted Detection of Colonic Lesions Using the iIDEAS Intelligent-C Module

Skip to content The CRC Digest ▪ SCREENING Real-Time AI-Assisted Detection of Colonic Lesions Using the iIDEAS Intelligent-C Module A prospective single-center validation study (NCT05784935) tested the iIDEAS-C computer-aided detection system during colonoscopy, with co-primary endpoints of adenomas per colonoscopy and lesion-level miss rate. (JGH Open) This content is informational only

Non-Invasive Colorectal Cancer Screening Using Stool- and Blood-Based Tests

Skip to content The CRC Digest ▪ SCREENING Non-Invasive Colorectal Cancer Screening Using Stool- and Blood-Based Tests A new review synthesizes evidence on fecal immunochemical testing (FIT), multi-omics stool DNA-FIT, multi-omics stool RNA-FIT, and blood-based assays for asymptomatic individuals at average risk, emphasizing the distinction between cancer detection and advanced precancerous

Newer colonoscope models and texture enhancement imaging improve adenoma detection

Skip to content The CRC Digest ▪ SCREENING Newer colonoscope models and texture enhancement imaging improve adenoma detection Analysis of 28,459 colonoscopies aimed to identify clinical and technological factors most strongly associated with increased adenoma detection rate, including newer colonoscope models and texture and color enhancement imaging. (Scand J Gastroenterol)

Prospective study examines MSI and CD8+ TILs in neoadjuvant chemotherapy response

Skip to content The CRC Digest Prospective study examines MSI and CD8+ TILs in neoadjuvant chemotherapy response A prospective observational study investigated whether microsatellite instability, CD8+ tumor infiltrating lymphocytes expression, and chemotherapy response are related in colorectal cancer patients receiving neoadjuvant treatment. (Cancer Manag Res) This content is informational only

AI algorithm stratifies stage II/IIIA colorectal cancer recurrence risk from standard pathology slides

Skip to content The CRC Digest ◇ RESEARCH AI algorithm stratifies stage II/IIIA colorectal cancer recurrence risk from standard pathology slides HistoNav, a deep-learning algorithm analyzing H&E-stained tissue samples from 2,095 patients, identified low-, intermediate-, and high-risk groups with 5-year disease-specific survival rates of 93.2%, 84.

AI-assisted colonoscopy systems standardize polyp detection accuracy

Skip to content The CRC Digest ▪ SCREENING AI-assisted colonoscopy systems standardize polyp detection accuracy Computer-aided detection and diagnosis systems using deep learning convolutional neural networks reduce inter-operator variability in adenoma detection rates and help identify diminutive and morphologically subtle lesions. (Journal of Clinical Medicine) This content is informational only and

Vietnamese CRC Survivors Report Significant Unmet Supportive Care Needs

Skip to content The CRC Digest ♥ LIVING WITH CRC Vietnamese CRC Survivors Report Significant Unmet Supportive Care Needs A cross-sectional study of 354 colorectal cancer survivors in Vietnam identified unmet supportive care needs following primary treatment, highlighting gaps in the healthcare system and cultural context. (European Journal of Oncology Nursing)