Immunotherapy May Reshape Fertility Counseling for Young Women with CRC Skip to content The CRC Digest Immunotherapy May Reshape Fertility Counseling for Young Women with CRC A narrative review found that immune checkpoint inhibitors for dMMR/MSI-H colorectal cancer may affect reproductive-age women through direct reproductive uncertainty (including endocrine toxicities and hypothesized, but currently unproven, direct gonadal effects) and potential
Validated Scale Helps Measure Treatment-Induced Neuropathy in Chinese Patients Skip to content The CRC Digest Validated Scale Helps Measure Treatment-Induced Neuropathy in Chinese Patients A prospective study of 254 colorectal cancer patients receiving oxaliplatin validated the Treatment-induced Neuropathy Assessment Scale (TNAS) and established cutpoints for numbness, sensory symptoms, and interference with daily activities. (Quality of Life Research) This content
Trimodal prehabilitation studied for anxiety and quality of life in CRC surgery Skip to content The CRC Digest Trimodal prehabilitation studied for anxiety and quality of life in CRC surgery An interim analysis of 45 patients (20 in prehabilitation, 25 in standard care) in a randomized trial evaluated whether a program combining exercise, nutrition, and psychological counseling could affect perioperative anxiety and
Inflammatory markers linked to fatigue up to 3 years after CRC surgery Skip to content The CRC Digest Inflammatory markers linked to fatigue up to 3 years after CRC surgery A multicenter study tracked 16 inflammatory biomarkers and fatigue in CRC patients from surgery through 36 months, finding longitudinal associations that may help identify patients at risk for persistent fatigue. (Cancer Medicine)
Latent Profile Analysis Identifies Distinct Quality of Life Patterns in CRC Survivors Skip to content The CRC Digest Latent Profile Analysis Identifies Distinct Quality of Life Patterns in CRC Survivors Researchers used latent profile analysis of EORTC quality of life questionnaires to identify distinct health-related quality of life profiles among colorectal cancer patients, aiming to inform more personalized follow-up strategies. (Colorectal Disease)
Anastomotic leakage shows minimal long-term impact on quality of life after rectal cancer surgery Skip to content The CRC Digest ♥ LIVING WITH CRC Anastomotic leakage shows minimal long-term impact on quality of life after rectal cancer surgery A Swedish population-based study found that while anastomotic leakage after anterior resection is associated with long-term bowel dysfunction, its impact on health-related quality of life 3 years