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retrospective

A collection of 3 issues

Prolonged Response to Pembrolizumab in BRAF V600E MSS Colorectal Cancer

Skip to content The CRC Digest Prolonged Response to Pembrolizumab in BRAF V600E MSS Colorectal Cancer A patient with BRAF V600E-mutant microsatellite-stable metastatic colorectal cancer achieved a prolonged response to pembrolizumab following a dynamic increase in tumor mutational burden. (The Oncologist) This content is informational only and does not constitute

Case Series Reports Bowel Narrowing as Rare Side Effect of Immunotherapy

Skip to content The CRC Digest Case Series Reports Bowel Narrowing as Rare Side Effect of Immunotherapy Doctors report cases of bowel stenosis (narrowing) in dMMR colorectal cancer patients treated with immunotherapy, a side effect that clinicians should monitor. (Clinical Colorectal Cancer) This content is informational only and does not

MSI-H tumor responds to immunotherapy while MSI-stable tumor does not in same patient

Skip to content The CRC Digest MSI-H tumor responds to immunotherapy while MSI-stable tumor does not in same patient Exceptional case of synchronous colon cancers with different MMR status provides direct in vivo evidence of ICI responsiveness differences. (Japanese Journal of Clinical Oncology) This content is informational only and does