Dynamic ctDNA Methylation Monitoring Guides Postoperative Surveillance in FIND Trial Skip to content The CRC Digest ◆ TRIAL DATA Dynamic ctDNA Methylation Monitoring Guides Postoperative Surveillance in FIND Trial A prospective, randomized phase III trial tested whether circulating tumor DNA methylation monitoring can guide postoperative surveillance in nonmetastatic colorectal cancer patients. (Journal of Clinical Oncology) This content is informational only and
Blood-based surveillance after surgery increased curative treatment for recurrence Skip to content The CRC Digest ▪ SCREENING Blood-based surveillance after surgery increased curative treatment for recurrence The phase III FIND trial showed that ctDNA methylation-guided surveillance in nonmetastatic colorectal cancer patients after surgery led to higher rates of curative-intent therapy for recurrence compared to standard CT-based monitoring. (Journal of Clinical
Updated Guidelines for Resectable Colorectal Cancer Published Skip to content The CRC Digest ● REGULATORY Updated Guidelines for Resectable Colorectal Cancer Published The American Society of Surgical Oncology summarized contemporary guidance from NCCN, ESMO, and JSCCR, highlighting recent evolution in molecular characterization (including mismatch repair status), neoadjuvant therapy, and organ-preservation strategies. (Ann Surg Oncol) This content is informational
Machine learning model predicts liver metastasis risk after colorectal cancer surgery Skip to content The CRC Digest ◇ RESEARCH Machine learning model predicts liver metastasis risk after colorectal cancer surgery A multicenter study developed an AI-integrated model using clinical, laboratory, and CT imaging data to predict which stage I–III CRC patients will develop metachronous liver metastasis within 5 years after radical