Physical activity and sedentary behavior linked to cortisol rhythms in CRC survivors up to 1 year after treatment Skip to content The CRC Digest ♥ LIVING WITH CRC Physical activity and sedentary behavior linked to cortisol rhythms in CRC survivors up to 1 year after treatment Among 74 CRC survivors, accelerometer-assessed sedentary time and physical activity were longitudinally associated with diurnal cortisol patterns, which may influence fatigue, mood, and
Immunotherapy May Reshape Fertility Counseling for Young Women with CRC Skip to content The CRC Digest Immunotherapy May Reshape Fertility Counseling for Young Women with CRC A narrative review found that immune checkpoint inhibitors for dMMR/MSI-H colorectal cancer may affect reproductive-age women through direct reproductive uncertainty (including endocrine toxicities and hypothesized, but currently unproven, direct gonadal effects) and potential
Canadian Symposium Highlights Care Gaps for Early-Onset Cancer Patients Skip to content The CRC Digest Canadian Symposium Highlights Care Gaps for Early-Onset Cancer Patients The 2025 Early Age Onset Cancer Symposium identified critical gaps including diagnostic delays, screening eligibility criteria that no longer reflect current disease epidemiology, and insufficient age-appropriate infrastructure for patients under 50. (Curr Oncol) This content
End-of-Life Care Trends Show Shift Toward Home and Hospice Skip to content The CRC Digest End-of-Life Care Trends Show Shift Toward Home and Hospice Among 75,428 early-onset CRC decedents from 1999-2020, the proportion dying at home or hospice facilities increased from 48.3% to 66.6%, though disparities persist for Black patients. (Journal of Gastrointestinal Cancer) This content
Inflammatory markers linked to fatigue up to 3 years after CRC surgery Skip to content The CRC Digest Inflammatory markers linked to fatigue up to 3 years after CRC surgery A multicenter study tracked 16 inflammatory biomarkers and fatigue in CRC patients from surgery through 36 months, finding longitudinal associations that may help identify patients at risk for persistent fatigue. (Cancer Medicine)
Latent Profile Analysis Identifies Distinct Quality of Life Patterns in CRC Survivors Skip to content The CRC Digest Latent Profile Analysis Identifies Distinct Quality of Life Patterns in CRC Survivors Researchers used latent profile analysis of EORTC quality of life questionnaires to identify distinct health-related quality of life profiles among colorectal cancer patients, aiming to inform more personalized follow-up strategies. (Colorectal Disease)