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Skip to content The CRC Digest Immunotherapy Shows Response in Pediatric CMMRD-Associated CRC A 10-year-old with constitutional mismatch repair deficiency-associated colorectal adenocarcinoma received neoadjuvant ipilimumab and nivolumab, achieving partial response. (Journal of Pediatric Hematology/Oncology) This content is informational only and does not constitute medical advice. Always consult your oncologist