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under-50

A collection of 94 issues

Screening strategies may not adequately address early-onset CRC burden

Skip to content The CRC Digest Screening strategies may not adequately address early-onset CRC burden A systematic review found uncertainty remains regarding whether current screening strategies adequately address the diagnostic burden of early-onset colorectal cancer, defined as diagnosis before age 50. (Cancer Epidemiol) This content is informational only and does

Systematic review finds screening gaps in early-onset colorectal cancer despite lowered age thresholds

Skip to content The CRC Digest ▪ SCREENING Systematic review finds screening gaps in early-onset colorectal cancer despite lowered age thresholds A systematic review of population-based screening studies found that current strategies may not adequately address the diagnostic burden of colorectal cancer in adults younger than 50, even as several countries

CRC Research Update — September 15, 2026

Today's colorectal cancer research highlights

Early-onset and average-onset metastatic colorectal cancer share similar genomic landscapes

Skip to content The CRC Digest ◇ RESEARCH Early-onset and average-onset metastatic colorectal cancer share similar genomic landscapes An analysis of 1,892 patients found that major driver alterations. TP53, APC, and KRAS — occurred at comparable frequencies in metastatic colorectal cancer diagnosed before age 50 versus later, suggesting the diseases are

CRC Research Update — September 14, 2026

Today's colorectal cancer research highlights

Scoping Review Maps Global Variation in Early-Onset CRC Patterns

Skip to content The CRC Digest Scoping Review Maps Global Variation in Early-Onset CRC Patterns A scoping review of studies published 2019–2024 synthesized contemporary evidence on epidemiologic, molecular, and survival differences in early-onset colorectal cancer across regions and racial/ethnic groups. (Journal of Gastrointestinal Cancer) This content is informational

Peer-Led Campus Program Targets CRC Awareness Among Young Adults

Skip to content The CRC Digest Peer-Led Campus Program Targets CRC Awareness Among Young Adults GRACCE, a community-led ambassador-driven education program, recruited student ambassadors from five universities to deliver campus-based CRC education, addressing rising incidence among young adults. (Journal of Cancer Education) This content is informational only and does not

CRC Research Update — September 11, 2026

Today's colorectal cancer research highlights

Machine learning may enable early detection in under-50 population

Skip to content The CRC Digest Machine learning may enable early detection in under-50 population A review highlights that early-onset colorectal cancer incidence is rising fastest in the population below guideline-endorsed screening age, and blood-based liquid biopsy combined with machine learning offers a plausible route to early detection. (Frontiers in

CRC Research Update — September 07, 2026

Today's colorectal cancer research highlights