Researchers identified ZBTB7A as an m6A-modified transcription factor that promotes colorectal cancer liver metastasis, with METTL3-mediated m6A modification of ZBTB7A facilitating recognition by the m6A reader YTHDF1/3 complex. (Molecular Cancer)
Targeted m6A Demethylation of ZBTB7A Suppresses Liver Metastasis in Preclinical Models
The CRC Digest