Circulating microRNAs improve identification of high-risk adenomas in FIT-positive patients

▪ SCREENING

A Canadian study of 398 FIT-positive screening participants found that adding plasma microRNA analysis to baseline risk factors increased the ability to identify high-risk adenomas from an AUC of 0.61 to 0.82, achieving 95% sensitivity at a 20% threshold. (Cancer Epidemiol Biomarkers Prev)