Sign in Subscribe

crc-research

A collection of 715 issues

Cancer Survivors Face Elevated Risk of Developing Colorectal Cancer

Skip to content The CRC Digest ♥ LIVING WITH CRC Cancer Survivors Face Elevated Risk of Developing Colorectal Cancer A Canadian cohort study of 172,928 non-colorectal cancer survivors found they have an elevated risk of developing subsequent primary colorectal cancers compared to the cancer-free population, suggesting tailored screening approaches may

Liquid Biopsies Can Monitor CRC Progression and Detect Residual Disease

Skip to content The CRC Digest ▪ RESEARCH Liquid Biopsies Can Monitor CRC Progression and Detect Residual Disease A translational science review in JAMA reports that circulating tumor DNA (ctDNA) sequencing can identify gene variants to inform treatment selection in colorectal cancer, and that detecting ctDNA after curative intent therapy correlates

Intensified Total Neoadjuvant Therapy Improves Survival in High-Risk Rectal Cancer

Skip to content The CRC Digest ◆ TRIAL DATA Intensified Total Neoadjuvant Therapy Improves Survival in High-Risk Rectal Cancer A Chinese phase III trial of 458 patients with high-risk locally advanced rectal cancer found that integrating long-course radiotherapy with uninterrupted capecitabine and oxaliplatin chemotherapy (doublet-LC TNT) achieved 3-year disease-free survival of

CRC Research Update — August 09, 2026

Today's colorectal cancer research highlights

ctDNA-Guided Treatment Decisions Show Mixed Results in Stage II and III Colon Cancer

Skip to content The CRC Digest ctDNA-Guided Treatment Decisions Show Mixed Results in Stage II and III Colon Cancer DYNAMIC-III found that escalation in ctDNA-positive stage III patients did not improve outcomes. (EClinicalMedicine) This content is informational only and does not constitute medical advice. Always consult your oncologist or care

Early Palliative Care Contact Linked to Reduced End-of-Life Healthcare Use

Skip to content The CRC Digest ♥ LIVING WITH CRC Early Palliative Care Contact Linked to Reduced End-of-Life Healthcare Use A nationwide Finnish study found that early specialist palliative care involvement (more than 30 days before death) was associated with lower healthcare utilization at end of life in patients with colorectal

Study Evaluates Trifluridine/Tipiracil in MSI-H/dMMR Metastatic CRC

Skip to content The CRC Digest ▸ TREATMENT Study Evaluates Trifluridine/Tipiracil in MSI-H/dMMR Metastatic CRC A study across 10 Japanese hospitals aimed to evaluate trifluridine/tipiracil (with or without bevacizumab) in MSI-H/dMMR metastatic colorectal cancer, a population known to resist standard fluorouracil-based therapies. (Therapeutic Advances in Medical Oncology)

ctDNA Shows Promise for Risk Stratification but Mixed Results for Treatment Selection

Skip to content The CRC Digest ◇ RESEARCH ctDNA Shows Promise for Risk Stratification but Mixed Results for Treatment Selection A review of circulating tumor DNA in GI cancers found that while postoperative ctDNA positivity identifies high-risk patients, recent trials show mixed results: DYNAMIC-III showed escalation in ctDNA-positive stage III disease

13-Year NordICC Data Show Colonoscopy Reduces CRC Incidence but Not Mortality

Skip to content The CRC Digest ▪ SCREENING 13-Year NordICC Data Show Colonoscopy Reduces CRC Incidence but Not Mortality Long-term follow-up from the NordICC trial comparing colonoscopy to no screening found a reduction in colorectal cancer incidence but no statistically significant mortality benefit at 13 years. (Gastroenterology) This content is informational

CRC Research Update — August 08, 2026

Today's colorectal cancer research highlights