Baseline ctDNA profiling informs HER2-targeted therapy outcomes Skip to content The CRC Digest Baseline ctDNA profiling informs HER2-targeted therapy outcomes TRIUMPH/MyPathway analysis shows baseline circulating tumor DNA and prior anti-EGFR therapy affect pertuzumab plus trastuzumab efficacy in HER2-amplified metastatic colorectal cancer. (ESMO Open) This content is informational only and does not constitute medical advice. Always consult
ctDNA clearance as early biomarker in KRAS G12C colorectal cancer Skip to content The CRC Digest ctDNA clearance as early biomarker in KRAS G12C colorectal cancer Phase 3 CodeBreaK 300 results link circulating tumor DNA clearance to efficacy and prognosis with sotorasib plus panitumumab. (JCO) This content is informational only and does not constitute medical advice. Always consult your oncologist
Practical guidance for integrating ctDNA testing into clinical care Skip to content The CRC Digest Practical guidance for integrating ctDNA testing into clinical care A narrative review summarizes evidence for ctDNA minimal residual disease testing in gastrointestinal cancers, with strongest data supporting use in resected stage II colon cancer. (Clinical and Translational Oncology) This content is informational only and
Circulating Tumor DNA Shows Promise for Predicting Colorectal Cancer Recurrence Skip to content The CRC Digest Circulating Tumor DNA Shows Promise for Predicting Colorectal Cancer Recurrence A review of current evidence suggests circulating tumor DNA has significant prognostic and predictive potential for detecting minimal residual disease and individualizing adjuvant therapy in colorectal cancer. (Klinická Onkologie) This content is informational only