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ctdna

A collection of 97 issues

Blood Test Combining cfDNA Fragmentomics and Methylation Markers Detects Precancerous Lesions

Skip to content The CRC Digest ▪ SCREENING Blood Test Combining cfDNA Fragmentomics and Methylation Markers Detects Precancerous Lesions A study of 380 CRC patients, 121 individuals with precancerous lesions, and 506 healthy controls found that adding methylation analysis of SEPT9 and HS3ST2 to cfDNA fragmentomic features improved detection of precancerous

CRC Research Update — August 27, 2026

Today's colorectal cancer research highlights

Circulating Tumor DNA Shows Promise for Guiding Adjuvant Therapy After Curative Surgery

Skip to content The CRC Digest ◇ RESEARCH Circulating Tumor DNA Shows Promise for Guiding Adjuvant Therapy After Curative Surgery A review examines how circulating tumor DNA (ctDNA) offers a dynamic readout of molecular residual disease in the postoperative period, potentially guiding adjuvant treatment decision-making in stage II (15-20% recurrence) and

CRC Research Update — August 25, 2026

Today's colorectal cancer research highlights

Liquid biopsy may redefine surgical decision-making in colorectal cancer

Skip to content The CRC Digest Liquid biopsy may redefine surgical decision-making in colorectal cancer A scoping review found that liquid biopsy offers a dynamic measure of tumor biology that complements pathological staging and guides postoperative management beyond conventional anatomy-based risk stratification. (Updates in Surgery) This content is informational only

ctDNA Testing May Identify Who Benefits from Chemotherapy After Liver Metastasis Surgery

Skip to content The CRC Digest ctDNA Testing May Identify Who Benefits from Chemotherapy After Liver Metastasis Surgery An overall survival analysis of the phase II GALAXY study presented at ESMO GI 2026 suggests that circulating tumor DNA for molecular residual disease tracking could help identify patients with colorectal cancer

CRC Research Update — August 24, 2026

Today's colorectal cancer research highlights

CRC Research Update — August 23, 2026

Today's colorectal cancer research highlights

Circulating tumor DNA dynamics predict survival in metastatic colorectal cancer

Skip to content The CRC Digest ◇ RESEARCH Circulating tumor DNA dynamics predict survival in metastatic colorectal cancer In a study of 1,391 patients, those with persistent or acquired RAS and BRAF mutations in ctDNA had significantly worse overall survival than patients who maintained wild-type status, suggesting liquid biopsy monitoring

CRC Research Update — August 22, 2026

Today's colorectal cancer research highlights