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liquid-biopsy

A collection of 68 issues

Salivary microbiome evaluated as non-invasive screening tool for early-onset CRC

Skip to content The CRC Digest Salivary microbiome evaluated as non-invasive screening tool for early-onset CRC High-throughput 16S ribosomal RNA gene sequencing of saliva samples showed distinct microbiota profiles in EOCRC patients compared to controls. (BMC Microbiol) This content is informational only and does not constitute medical advice. Always consult

Study examines colonoscopy impact in older adults with borderline FIT values

Skip to content The CRC Digest Study examines colonoscopy impact in older adults with borderline FIT values Researchers used a regression discontinuity design to investigate whether CRC screening affects incidence among 2,773 adults aged 71-75 with FIT values between 80-120 ng/ml. (Int J Epidemiol) This content is informational

Salivary microbiome profiles distinguish early-onset CRC patients from healthy controls

Skip to content The CRC Digest Salivary microbiome profiles distinguish early-onset CRC patients from healthy controls Researchers collected saliva samples from 65 EOCRC patients and 63 controls, profiling the microbiota and developing screening models using machine learning algorithms. (BMC Microbiol) This content is informational only and does not constitute medical

Liquid Biopsy Platform Now Detects Early-Stage Disease

Skip to content The CRC Digest Liquid Biopsy Platform Now Detects Early-Stage Disease Plasmonic technology expanded to early-stage colorectal cancer. (EurekAlert) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com

National Study Examines Follow-Up Colonoscopy Rates After Positive Stool Tests by Race and Ethnicity

Skip to content The CRC Digest National Study Examines Follow-Up Colonoscopy Rates After Positive Stool Tests by Race and Ethnicity A retrospective cohort study linking national data from 2016 to 2023 evaluated follow-up colonoscopy rates, time to colonoscopy, and compliance predictors after positive FIT, FOBT, or mt-sDNA tests, noting that

Review examines liquid biopsy potential and limitations for CRC screening

Skip to content The CRC Digest Review examines liquid biopsy potential and limitations for CRC screening Analysis notes promise of circulating tumor DNA and cells for detection but highlights limited sensitivity for advanced adenomas and lack of randomized trial evidence for mortality reduction. (Intestinal Research) This content is informational only

New blood test achieves 60% sensitivity for early-stage cancers

Skip to content The CRC Digest New blood test achieves 60% sensitivity for early-stage cancers Caris Detect combines whole genome sequencing and AI; ACHIEVE 1 study showed 60.3% sensitivity for stage I-II cancers including colorectal. (Fierce Biotech) This content is informational only and does not constitute medical advice. Always

CRC Research Finding

Skip to content The CRC Digest ▪ Personalized ctDNA Test Detects Stage III Recurrence Before Imaging A case series of four stage III CRC patients showed the Signatera ctDNA assay detected recurrence earlier than imaging and informed curative interventions. (Cancer Diagnosis & Prognosis) This content is informational only and does not

French multicenter study to evaluate ctDNA after liver metastasis surgery

Skip to content The CRC Digest French multicenter study to evaluate ctDNA after liver metastasis surgery The CLIMES PRODIGE 77 study will enroll 232 patients undergoing curative-intent liver metastasis resection to evaluate circulating tumor DNA as a biomarker for detecting minimal residual disease and predicting prognosis. (BMJ Open) This content

ColoSense RNA-Based At-Home Test

Skip to content The CRC Digest ColoSense RNA-Based At-Home Test First FDA-approved RNA-based at-home screening test now available nationwide through Labcorp. This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026 The CRC Digest — crcdigest.com