Prognostic Factors in Young Patients with Liver Metastases Skip to content The CRC Digest Prognostic Factors in Young Patients with Liver Metastases A SEER database study of 2,222 patients with colorectal liver metastases compared disease-specific survival in those under 45 versus 45 and older who underwent colon and liver resection from 2010 to 2021. (J Surg Oncol)
CRC Research Finding Skip to content The CRC Digest ◇ Single-cell analysis identifies epithelial cell fate signature predicting liver metastasis risk Researchers integrated single-cell RNA sequencing of paired liver metastasis tissues to define an epithelial cell fate gene signature, then projected it onto 433 primary CRC cases to establish a predictive model for liver
ABFOLFOX neoadjuvant therapy studied in unresectable liver metastases Skip to content The CRC Digest ◆ TRIAL DATA ABFOLFOX neoadjuvant therapy studied in unresectable liver metastases — Genome Medicine A study examined neoadjuvant ABFOLFOX (atezolizumab, bevacizumab, leucovorin, 5-fluorouracil, and oxaliplatin) in patients with unresectable colorectal liver metastases. The research explored molecular dynamics of tumor ecosystems and their impact on treatment outcomes.