Gut bacterium Eggerthella lenta linked to liver metastasis via vascular barrier disruption Skip to content The CRC Digest ◇ RESEARCH Gut bacterium Eggerthella lenta linked to liver metastasis via vascular barrier disruption Multi-omics analysis of two cohorts comprising 20 healthy controls, 82 non-metastatic CRC patients, and 65 patients with liver or lung metastases found that those with CRC liver metastasis had impaired gut
Pathological complete response to pembrolizumab in dMMR CRC despite radiological residual disease Skip to content The CRC Digest Pathological complete response to pembrolizumab in dMMR CRC despite radiological residual disease A case report describes a 70-year-old man with dMMR sigmoid colon cancer and liver metastases who achieved pathological complete response in both primary and metastatic lesions after preoperative pembrolizumab, despite imaging suggesting
Pooled Analysis Examines Prognostic Value of KRAS Mutations and Liver Metastases Skip to content The CRC Digest Pooled Analysis Examines Prognostic Value of KRAS Mutations and Liver Metastases A pooled analysis of third-line placebo-controlled trials from the ARCAD CRC Database evaluated the prognostic impact of liver metastases and KRAS mutations in metastatic colorectal cancer patients. (Clinical Colorectal Cancer) This content is