CRC Research Update — June 15, 2026
Today's colorectal cancer research highlights
metastatic
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CRC Research Finding
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The CRC Digest
◇ Loss of Y chromosome in primary tumors analyzed in metastatic CRC patients
A retrospective study of 91 male patients with metastatic CRC examined tumor-associated loss of the Y chromosome (LoY) and its associations with KRAS/BRAF mutation status and patient outcomes. (Genes Chromosomes Cancer)
CRC Research Update — June 10, 2026
Today's colorectal cancer research highlights
BRAF V600E screening identifies candidates for perioperative therapy
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The CRC Digest
BRAF V600E screening identifies candidates for perioperative therapy
Multicenter screening evaluated preoperative BRAF V600E mutation detection in patients with resectable colorectal oligometastases, enabling recruitment to a trial of the BEACON triplet regimen. (Int J Clin Oncol)
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CRC Research Update — June 09, 2026
Today's colorectal cancer research highlights
CRC Research Update — June 07, 2026
Today's colorectal cancer research highlights
CRC Research Update — June 06, 2026
Today's colorectal cancer research highlights
CRC Research Update — June 04, 2026
Today's colorectal cancer research highlights
CRC Research Update — June 01, 2026
Today's colorectal cancer research highlights
BRAF V600E triplet regimen advances in phase 3 trial
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The CRC Digest
BRAF V600E triplet regimen advances in phase 3 trial
BREAKWATER Cohort 3 evaluated encorafenib + cetuximab + FOLFIRI versus FOLFIRI ± bevacizumab in previously untreated BRAF V600E-mutant mCRC, with primary endpoint of objective response rate and key secondary endpoint of progression-free survival. (Annals of Oncology)
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