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prospective

A collection of 92 issues

Resourcefulness May Buffer Stress and Improve Quality of Life for Ostomy Patients

Skip to content The CRC Digest ♥ LIVING WITH CRC Resourcefulness May Buffer Stress and Improve Quality of Life for Ostomy Patients A cross-sectional study of 464 colorectal cancer patients with intestinal ostomy found that resourcefulness mediated the relationship between perceived stress and quality of life, suggesting a potential target for

Younger CRC Patients Face Distinct Quality of Life Challenges

Skip to content The CRC Digest Younger CRC Patients Face Distinct Quality of Life Challenges A qualitative study comparing early-onset colorectal cancer patients to older patients found that young people with colorectal cancer experience worse psychological wellbeing, including marked emotional distress and prominent levels of anxiety. (Quality of Life Research)

AHN researchers help develop blood test that detects colorectal cancer and high-risk polyps

Skip to content The CRC Digest ▪ SCREENING AHN researchers help develop blood test that detects colorectal cancer and high-risk polyps Researchers at Allegheny Health Network contributed to development of a blood-based screening test capable of detecting both colorectal cancer and high-risk polyps. (Beaver County Radio) This content is informational only

Qualitative study explores barriers and facilitators to exercise in older adults with colorectal cancer

Skip to content The CRC Digest Qualitative study explores barriers and facilitators to exercise in older adults with colorectal cancer Researchers interviewed patients aged 75 years or older with CRC scheduled for elective surgery to understand what helps or hinders participation in physical exercise during the perioperative period, noting that

Blood test shows promise for detecting advanced adenomas and colorectal cancer

Skip to content The CRC Digest ▪ SCREENING Blood test shows promise for detecting advanced adenomas and colorectal cancer The DENEB study developed and evaluated a novel blood-based assay designed to detect both advanced adenomas and colorectal cancer, addressing a key limitation of current blood tests by targeting premalignant lesions essential

Study identifies distinct stigma profiles among colorectal cancer patients with ostomies

Skip to content The CRC Digest ♥ LIVING WITH CRC Study identifies distinct stigma profiles among colorectal cancer patients with ostomies A cross-sectional survey of 449 patients with colorectal cancer and intestinal ostomy used latent profile analysis to identify stigma subtypes and found that stoma acceptance mediates the relationship between stigma

Gut microbiome and metabolite profiles differ between immunotherapy responders and non-responders

Skip to content The CRC Digest ◇ RESEARCH Gut microbiome and metabolite profiles differ between immunotherapy responders and non-responders In 20 patients with MSI-H advanced colorectal cancer receiving immunotherapy, metagenomic sequencing and metabolomics revealed distinct gut microbiota and metabolite patterns associated with clinical benefit versus non-benefit, suggesting the microbiome may influence

Study Examines Universal Tumor Screening for Lynch Syndrome in Japan

Skip to content The CRC Digest ▪ SCREENING Study Examines Universal Tumor Screening for Lynch Syndrome in Japan A prospective study of 591 patients with stage II/III colorectal cancer in Japan aimed to clarify the clinical utility and cost-effectiveness of universal tumor screening using immunohistochemistry to identify Lynch syndrome, with

Lean Body Mass Linked to Oxaliplatin Neuropathy Risk

Skip to content The CRC Digest ♥ LIVING WITH CRC Lean Body Mass Linked to Oxaliplatin Neuropathy Risk A study of colorectal cancer patients receiving adjuvant CAPOX found that lean body mass and sarcopenia may influence the risk of dose-limiting peripheral neuropathy, suggesting current body-surface-area dosing may not account for important

Physical activity and sedentary behavior linked to cortisol rhythms in CRC survivors up to 1 year after treatment

Skip to content The CRC Digest ♥ LIVING WITH CRC Physical activity and sedentary behavior linked to cortisol rhythms in CRC survivors up to 1 year after treatment Among 74 CRC survivors, accelerometer-assessed sedentary time and physical activity were longitudinally associated with diurnal cortisol patterns, which may influence fatigue, mood, and