Long-term outcomes reported for neoadjuvant bevacizumab and chemoradiotherapy in locally advanced rectal cancer Skip to content The CRC Digest ▸ TREATMENT Long-term outcomes reported for neoadjuvant bevacizumab and chemoradiotherapy in locally advanced rectal cancer A multicentre study followed patients treated with bevacizumab combined with chemoradiation before surgery for locally advanced rectal cancer. (Clinical Colorectal Cancer) This content is informational only and does not constitute
Baseline ctDNA analyzed for thrombotic risk in locally advanced rectal cancer Skip to content The CRC Digest Baseline ctDNA analyzed for thrombotic risk in locally advanced rectal cancer Plasma ctDNA was analyzed by droplet digital PCR for tumor-specific mutations including KRAS, NRAS, BRAF, and PIK3CA to explore association with VTE occurrence. (Cancer Treat Res Commun) This content is informational only and
Jemperli Shows Sustained Response in dMMR/MSI-H Rectal Cancer Skip to content The CRC Digest Jemperli Shows Sustained Response in dMMR/MSI-H Rectal Cancer Phase 2 data support potential organ preservation in patients with mismatch repair deficient tumors. (Fierce Pharma) This content is informational only and does not constitute medical advice. Always consult your oncologist or care team. © 2026
Sotorasib Plus Panitumumab Produces Response in Rare NRAS G12C-Mutated MSI-H Rectal Cancer Skip to content The CRC Digest Sotorasib Plus Panitumumab Produces Response in Rare NRAS G12C-Mutated MSI-H Rectal Cancer A case report describes an objective tumor response to the KRAS G12C inhibitor sotorasib combined with EGFR blockade in a patient with advanced NRAS G12C-mutated, mismatch repair-deficient rectal adenocarcinoma refractory to immunotherapy.
Pelvic floor rehabilitation addresses bowel dysfunction and quality of life after rectal cancer Skip to content The CRC Digest Pelvic floor rehabilitation addresses bowel dysfunction and quality of life after rectal cancer Fourteen survivors shared experiences with structured pelvic floor programs that support bowel function recovery and address psychosocial impacts of low anterior resection syndrome. (Support Care Cancer) This content is informational only
CRC Research Finding Skip to content The CRC Digest ♥ Structured pelvic floor rehabilitation helps survivors manage bowel dysfunction after rectal cancer surgery A qualitative study of 14 colorectal cancer survivors found that structured pelvic floor rehabilitation programs address low anterior resection syndrome, a common challenge affecting bowel function, psychosocial health, and daily living