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screening-procedure

A collection of 113 issues

Multigene Panel Testing Yield Quantified in Colorectal Cancer Patients

Skip to content The CRC Digest ◇ RESEARCH Multigene Panel Testing Yield Quantified in Colorectal Cancer Patients A systematic review and meta-analysis examined the diagnostic yield of germline multigene panel testing using next-generation sequencing in unselected patients with colorectal cancer, helping clarify how often inherited genetic factors contribute to diagnosis. (Lancet

AI Tool Shows Promise for Scalable Colorectal Cancer Screening

Skip to content The CRC Digest ▪ SCREENING AI Tool Shows Promise for Scalable Colorectal Cancer Screening Researchers describe progress toward practical artificial intelligence applications that could expand access to colorectal cancer screening at scale. (Annals of Oncology) This content is informational only and does not constitute medical advice. Always consult

Developing Quality Programs to Track Colorectal Cancer Screening

Skip to content The CRC Digest Developing Quality Programs to Track Colorectal Cancer Screening A new article proposes features for an ideal tracking system to enhance screening program performance, noting that common issues include suboptimal return rates for stool-based tests, lack of timely colonoscopy after abnormal results, and surveillance recommendations

Review Outlines Advances and Challenges to Colonoscopy Quality

Skip to content The CRC Digest ▪ SCREENING Review Outlines Advances and Challenges to Colonoscopy Quality A new article in Gastrointestinal Endoscopy Clinics of North America outlines current advances, challenges, and best practices for high-quality colonoscopy, noting that colorectal cancer remains the third most common cancer by incidence and second most

Meta-Analysis Examines Fecal Immunochemical Test Accuracy

Skip to content The CRC Digest ▪ SCREENING Meta-Analysis Examines Fecal Immunochemical Test Accuracy A systematic review and meta-analysis evaluated the diagnostic accuracy of quantitative fecal immunochemical tests (FIT) for colorectal cancer and advanced neoplasm, examining variations in performance by sex, geographic region, study design, FIT platform, and positivity threshold. (Cancer

Blood-Based CRC Screening Tests Show Promise but Have Key Limitations

Skip to content The CRC Digest ▪ SCREENING Blood-Based CRC Screening Tests Show Promise but Have Key Limitations Three blood-based CRC screening tests (Epi proColon, Shield, and the Freenome test) have completed large validation studies, but all show low sensitivity for advanced precancerous lesions, low rates of follow-up colonoscopy after an

Screening Age Thresholds Miss Early-Onset CRC Risk Established in Youth

Skip to content The CRC Digest Screening Age Thresholds Miss Early-Onset CRC Risk Established in Youth A new analysis argues that age-based screening creates a "blind spot" for early-onset colorectal cancer because high-risk states may be established through early-life exposures decades before screening begins at age 45. (Frontiers

Computer-Aided Feedback System Evaluated for Colonoscopy Quality in Denmark

Skip to content The CRC Digest ▪ SCREENING Computer-Aided Feedback System Evaluated for Colonoscopy Quality in Denmark A stepped-wedge cluster-randomised trial across three Danish hospitals evaluated the effect of a computer-aided quality feedback and monitoring system on endoscopists' adenoma detection rate in patients aged 50-74 with positive FIT results. (The

AI-assisted colonoscopy cost-effectiveness study evaluates financial impact in Singapore

Skip to content The CRC Digest ▪ SCREENING AI-assisted colonoscopy cost-effectiveness study evaluates financial impact in Singapore Computer-assisted detection (CADe) during screening colonoscopy improves adenoma detection rates while reducing endoscopists' mental fatigue. (Int J Surg) This content is informational only and does not constitute medical advice. Always consult your oncologist

First Colombian report of MUTYH-associated polyposis with novel mutations

Skip to content The CRC Digest ◇ RESEARCH First Colombian report of MUTYH-associated polyposis with novel mutations Case series from Colombia's Tolima Grande region describes individuals carrying pathogenic MUTYH variants c.452A>G and c.1353_1355del associated with polyposis phenotypes and colorectal cancer predisposition. (Frontiers in Oncology)