Sign in Subscribe

screening-procedure

A collection of 109 issues

Meta-Analysis Examines Fecal Immunochemical Test Accuracy

Skip to content The CRC Digest ▪ SCREENING Meta-Analysis Examines Fecal Immunochemical Test Accuracy A systematic review and meta-analysis evaluated the diagnostic accuracy of quantitative fecal immunochemical tests (FIT) for colorectal cancer and advanced neoplasm, examining variations in performance by sex, geographic region, study design, FIT platform, and positivity threshold. (Cancer

Blood-Based CRC Screening Tests Show Promise but Have Key Limitations

Skip to content The CRC Digest ▪ SCREENING Blood-Based CRC Screening Tests Show Promise but Have Key Limitations Three blood-based CRC screening tests (Epi proColon, Shield, and the Freenome test) have completed large validation studies, but all show low sensitivity for advanced precancerous lesions, low rates of follow-up colonoscopy after an

Screening Age Thresholds Miss Early-Onset CRC Risk Established in Youth

Skip to content The CRC Digest Screening Age Thresholds Miss Early-Onset CRC Risk Established in Youth A new analysis argues that age-based screening creates a "blind spot" for early-onset colorectal cancer because high-risk states may be established through early-life exposures decades before screening begins at age 45. (Frontiers

Computer-Aided Feedback System Evaluated for Colonoscopy Quality in Denmark

Skip to content The CRC Digest ▪ SCREENING Computer-Aided Feedback System Evaluated for Colonoscopy Quality in Denmark A stepped-wedge cluster-randomised trial across three Danish hospitals evaluated the effect of a computer-aided quality feedback and monitoring system on endoscopists' adenoma detection rate in patients aged 50-74 with positive FIT results. (The

AI-assisted colonoscopy cost-effectiveness study evaluates financial impact in Singapore

Skip to content The CRC Digest ▪ SCREENING AI-assisted colonoscopy cost-effectiveness study evaluates financial impact in Singapore Computer-assisted detection (CADe) during screening colonoscopy improves adenoma detection rates while reducing endoscopists' mental fatigue. (Int J Surg) This content is informational only and does not constitute medical advice. Always consult your oncologist

First Colombian report of MUTYH-associated polyposis with novel mutations

Skip to content The CRC Digest ◇ RESEARCH First Colombian report of MUTYH-associated polyposis with novel mutations Case series from Colombia's Tolima Grande region describes individuals carrying pathogenic MUTYH variants c.452A>G and c.1353_1355del associated with polyposis phenotypes and colorectal cancer predisposition. (Frontiers in Oncology)

Single colonoscopy screening invitation reduces colorectal cancer incidence but not mortality at 13 years

Skip to content The CRC Digest ▪ SCREENING Single colonoscopy screening invitation reduces colorectal cancer incidence but not mortality at 13 years A long-term study found that a single colonoscopy screening invitation reduced CRC incidence compared to no invitation, but did not reduce cancer-related mortality at 13-year follow-up. (Ann Intern Med)

Whole-Genome Electrical Impedance Assay Detects DNA Hypomethylation for CRC Screening

Skip to content The CRC Digest ▪ SCREENING Whole-Genome Electrical Impedance Assay Detects DNA Hypomethylation for CRC Screening A rapid, label-free cell-free DNA assay measures global DNA hypomethylation—a hallmark of colorectal cancer—using electrical impedance to differentiate healthy individuals from those with cancer in a retrospective validation study. (Computational and

Digital Platform Validated for Colorectal Cancer Risk Stratification and Personalized Screening Recommendations

Skip to content The CRC Digest Digital Platform Validated for Colorectal Cancer Risk Stratification and Personalized Screening Recommendations Validation study of ChequeáTuColon, a digital tool designed to stratify colorectal cancer risk, detect alarm symptoms, and provide personalized guideline-based screening recommendations, shows accuracy when compared to expert gastroenterologist assessments. (Digestive Diseases

Blood-Based Immune Profiling Identifies Circulating Th1-Like Cells as Biomarker for Advanced Adenomas

Skip to content The CRC Digest Blood-Based Immune Profiling Identifies Circulating Th1-Like Cells as Biomarker for Advanced Adenomas Prospective study of 104 FOBT-positive patients used spectral cytometry and machine learning to identify circulating Th1-like cells as a potential blood biomarker to improve detection of advanced colorectal adenomas and optimize colonoscopy