Phase III trial shows circulating tumor DNA methylation monitoring can guide postoperative surveillance in nonmetastatic colorectal cancer Skip to content The CRC Digest ◆ TRIAL DATA Phase III trial shows circulating tumor DNA methylation monitoring can guide postoperative surveillance in nonmetastatic colorectal cancer The prospective, randomized FIND trial used dynamic ctDNA methylation monitoring to personalize follow-up care after surgery in stage I-III patients. (Journal of Clinical Oncology) This
Circulating Tumor DNA Shows Promise for Guiding Adjuvant Therapy After Curative Surgery Skip to content The CRC Digest ◇ RESEARCH Circulating Tumor DNA Shows Promise for Guiding Adjuvant Therapy After Curative Surgery A review examines how circulating tumor DNA (ctDNA) offers a dynamic readout of molecular residual disease in the postoperative period, potentially guiding adjuvant treatment decision-making in stage II (15-20% recurrence) and
HER2 amplification studied in resectable CRC Skip to content The CRC Digest HER2 amplification studied in resectable CRC A study of 3,607 patients with resectable colorectal cancer investigated the prognostic impact of WES-defined ERBB2 amplification and its association with adjuvant chemotherapy efficacy and circulating tumor DNA. (Int J Clin Oncol) This content is informational only