Colorectal neoplasia detected at young age in Li-Fraumeni syndrome surveillance

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In seven women with Li-Fraumeni syndrome, colorectal neoplasia was detected in five patients at a median age of 32.5 years, including one colorectal cancer at age 32 and three advanced adenomas; four patients developed lesions within 2-3 years after a negative baseline colonoscopy. (Clinical Journal of Gastroenterology)