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early-onset

A collection of 127 issues

Polyp Risk Rises with Age in Young Adults, Study Finds

Skip to content The CRC Digest Polyp Risk Rises with Age in Young Adults, Study Finds A retrospective colonoscopy study of 3,959 adults aged 18-44 used Joinpoint regression to identify age inflection points for polyp detection rates, with detection rates for polyps, adenomas, and serrated lesions all rising significantly

FIT Performance Data Now Available for Adults 55 and Younger

Skip to content The CRC Digest ▪ SCREENING FIT Performance Data Now Available for Adults 55 and Younger A cross-sectional German study of 1,724 participants aged 55 or younger assessed fecal immunochemical test (FIT) diagnostic performance at various fecal hemoglobin cutoffs for detecting advanced neoplasia, addressing a critical data gap

CRC Research Update — July 27, 2026

Today's colorectal cancer research highlights

End-of-Life Care Trends Show Shift Toward Home and Hospice

Skip to content The CRC Digest End-of-Life Care Trends Show Shift Toward Home and Hospice Among 75,428 early-onset CRC decedents from 1999-2020, the proportion dying at home or hospice facilities increased from 48.3% to 66.6%, though disparities persist for Black patients. (Journal of Gastrointestinal Cancer) This content

China Issues Expert Consensus on Early-Onset CRC Management

Skip to content The CRC Digest China Issues Expert Consensus on Early-Onset CRC Management New guidelines address the unique needs of younger patients, including fertility preservation, sexual function, and long-term quality of life considerations. (Zhonghua Wei Chang Wai Ke Za Zhi) This content is informational only and does not constitute

Pediatric Colorectal Cancer in Africa: Multicenter Study Reveals Late Diagnosis

Skip to content The CRC Digest Pediatric Colorectal Cancer in Africa: Multicenter Study Reveals Late Diagnosis A 14-country African study of 108 children and adolescents (mean age 14.9 years) diagnosed with CRC found a mean symptom-to-diagnosis duration of 90 days, with most presenting with abdominal discomfort and bowel habit

CRC Research Update — July 25, 2026

Today's colorectal cancer research highlights

Metastatic CRC Diagnosed Before Age 35 May Be a Distinct Subset

Skip to content The CRC Digest Metastatic CRC Diagnosed Before Age 35 May Be a Distinct Subset An Australasian registry study compared demographic and clinicopathologic characteristics of metastatic colorectal cancer patients diagnosed before age 35 with those diagnosed at 35–49 years and ≥50 years. (International Journal of Cancer) This

CRC Research Update — July 19, 2026

Today's colorectal cancer research highlights

Case-control study compares metabolic and laboratory biomarkers in early-onset versus late-onset colorectal cancer

Skip to content The CRC Digest Case-control study compares metabolic and laboratory biomarkers in early-onset versus late-onset colorectal cancer Researchers used a large US database to compare metabolic, inflammatory, and laboratory abnormalities between patients diagnosed at ages 18-49 versus 50-75. (Cancers) This content is informational only and does not constitute