CRC Research Update

  • SCREENING

    American Cancer Society adds blood-based tests to CRC screening guidelines

    In May 2026, the American Cancer Society updated their recommendations to include blood-based tests for individuals who decline or do not complete preferred screening tests, with a colonoscopy within 6 months required for positive results. (Lancet Gastroenterology & Hepatology)

  • RESEARCH

    Real-world data on HER2-positive metastatic CRC from 14 Japanese centers

    A multicenter retrospective study of 45 patients with HER2-positive metastatic colorectal cancer diagnosed between 2010 and 2023 examined outcomes with different first-line targeted agents and assessed safety of trastuzumab plus pertuzumab. (International Journal of Clinical Oncology)

  • LIVING WITH CRC

    Smartphone-based education program for family caregivers of CRC patients

    A randomized controlled trial of 80 family caregivers of CRC patients tested a smartphone-based educational program designed to meet supportive care needs compared to routine care, with assessments completed before and 4 weeks after the intervention. (Supportive Care in Cancer)

  • LIVING WITH CRC

    Pre-chemotherapy anxiety and sleep disturbance linked to immune changes and quality of life

    A prospective study of 268 CRC patients assessed within 24 hours before their first chemotherapy cycle found that anxiety-sleep disturbance symptoms were associated with neuroendocrine dysregulation, cellular immune alterations, and quality of life, with cortisol and IL-6 acting as biological mediators. (Neuroimmunomodulation)

🔬 Under 50 Spotlight

Research relevant to early-onset and younger CRC patients

🔎 Screening Watch

Screening guidelines, early detection, and prevention advances

Research continues to expand screening options and support for patients and caregivers navigating CRC.