Pooled Analysis Examines Prognostic Value of KRAS Mutations and Liver Metastases Skip to content The CRC Digest Pooled Analysis Examines Prognostic Value of KRAS Mutations and Liver Metastases A pooled analysis of third-line placebo-controlled trials from the ARCAD CRC Database evaluated the prognostic impact of liver metastases and KRAS mutations in metastatic colorectal cancer patients. (Clinical Colorectal Cancer) This content is
Circulating Tumor DNA Predicts Recurrence After Liver Metastasis Resection Skip to content The CRC Digest ◇ RESEARCH Circulating Tumor DNA Predicts Recurrence After Liver Metastasis Resection A systematic review and meta-analysis found that circulating tumor DNA (ctDNA) serves as a biomarker for recurrence after curative resection of colorectal cancer liver metastases, potentially guiding post-surgical surveillance strategies. (Clinical Colorectal Cancer) This
Targeted m6A Demethylation of ZBTB7A Suppresses Liver Metastasis in Preclinical Models Skip to content The CRC Digest Targeted m6A Demethylation of ZBTB7A Suppresses Liver Metastasis in Preclinical Models Researchers identified ZBTB7A as an m6A-modified transcription factor that promotes colorectal cancer liver metastasis, with METTL3-mediated m6A modification of ZBTB7A facilitating recognition by the m6A reader YTHDF1/3 complex. (Molecular Cancer) This content