Machine learning model predicts liver metastasis risk after colorectal cancer surgery Skip to content The CRC Digest ◇ RESEARCH Machine learning model predicts liver metastasis risk after colorectal cancer surgery A multicenter study developed an AI-integrated model using clinical, laboratory, and CT imaging data to predict which stage I–III CRC patients will develop metachronous liver metastasis within 5 years after radical
Circulating tumor DNA may identify which patients benefit from chemotherapy after liver metastasis surgery Skip to content The CRC Digest ◆ TRIAL DATA Circulating tumor DNA may identify which patients benefit from chemotherapy after liver metastasis surgery The phase II GALAXY study (298 patients) found that ctDNA testing 2-10 weeks after surgery for colorectal liver metastases could help predict which patients are most likely to
RAS mutation linked to early progression in liver metastases conversion therapy Skip to content The CRC Digest RAS mutation linked to early progression in liver metastases conversion therapy Retrospective study of 194 patients with initially unresectable, pMMR colorectal liver metastases found that RAS mutation status was associated with early progression or recurrence after conversion therapy. (Front Surg) This content is informational
CRC Research Finding Skip to content The CRC Digest ▸ Meta-Analysis Confirms Targeted Therapy Benefits for Colorectal Cancer Liver Metastases A systematic review and meta-analysis evaluated targeted therapy in colorectal cancer liver metastases, examining overall survival, progression-free survival, objective response rate, and conversion to resection. The analysis provides comprehensive evidence on the role of